DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hyun Jae Jang | - |
dc.contributor.author | Hyun-Mee Oh | - |
dc.contributor.author | Joo Tae Hwang | - |
dc.contributor.author | Mi Hwa Kim | - |
dc.contributor.author | Soyoung Lee | - |
dc.contributor.author | Kyungsook Jung | - |
dc.contributor.author | Y H Kim | - |
dc.contributor.author | Seung Woong Lee | - |
dc.contributor.author | Mun Chual Rho | - |
dc.date.accessioned | 2017-04-19T10:26:26Z | - |
dc.date.available | 2017-04-19T10:26:26Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0031-9422 | - |
dc.identifier.uri | 10.1016/j.phytochem.2016.08.001 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/13412 | - |
dc.description.abstract | Seven eudesmane-type sesquiterpenoid lactones and the known plebeiolide C were isolated from an ethanol-soluble extract of the aerial parts of Salvia plebeia R. Br. Their structures were determined via NMR and MS, and their absolute configurations were elucidated using ECD, and X-ray crystallographic analysis, as well as the modified Mosher ester method. All isolates were evaluated for their inhibitory effects on IL6-induced STAT3 promoter activation in stably transfected Hep3B cells. Of these isolates, eudebeiolide D exhibited an inhibitory effect with the IC50 value of 1.1?μM. | - |
dc.publisher | Elsevier | - |
dc.title | Eudesmane-type sesquiterpenoids from Salvia plebeia inhibit IL-6-induced STAT3 activation = 곰보배추로부터 분리된 유데스만계 세스퀴테르페노이드 화합물의 IL-6 유도 STAT3 활성 저해 | - |
dc.title.alternative | Eudesmane-type sesquiterpenoids from Salvia plebeia inhibit IL-6-induced STAT3 activation | - |
dc.type | Article | - |
dc.citation.title | Phytochemistry | - |
dc.citation.number | 0 | - |
dc.citation.endPage | 342 | - |
dc.citation.startPage | 335 | - |
dc.citation.volume | 130 | - |
dc.contributor.affiliatedAuthor | Hyun Jae Jang | - |
dc.contributor.affiliatedAuthor | Hyun-Mee Oh | - |
dc.contributor.affiliatedAuthor | Joo Tae Hwang | - |
dc.contributor.affiliatedAuthor | Mi Hwa Kim | - |
dc.contributor.affiliatedAuthor | Soyoung Lee | - |
dc.contributor.affiliatedAuthor | Kyungsook Jung | - |
dc.contributor.affiliatedAuthor | Seung Woong Lee | - |
dc.contributor.affiliatedAuthor | Mun Chual Rho | - |
dc.contributor.alternativeName | 장현재 | - |
dc.contributor.alternativeName | 오현미 | - |
dc.contributor.alternativeName | 황주태 | - |
dc.contributor.alternativeName | 김미화 | - |
dc.contributor.alternativeName | 이소영 | - |
dc.contributor.alternativeName | 정경숙 | - |
dc.contributor.alternativeName | 김영호 | - |
dc.contributor.alternativeName | 이승웅 | - |
dc.contributor.alternativeName | 노문철 | - |
dc.identifier.bibliographicCitation | Phytochemistry, vol. 130, pp. 335-342 | - |
dc.identifier.doi | 10.1016/j.phytochem.2016.08.001 | - |
dc.subject.keyword | Salvia plebeia | - |
dc.subject.keyword | Lamiaceae | - |
dc.subject.keyword | Eudesmane sesquiterpenoids | - |
dc.subject.keyword | IL-6 | - |
dc.subject.keyword | STAT3 | - |
dc.subject.keyword | Inflammation | - |
dc.subject.local | Salvia plebeia | - |
dc.subject.local | Lamiaceae | - |
dc.subject.local | Eudesmane sesquiterpenoids | - |
dc.subject.local | IL6 | - |
dc.subject.local | interukin -6 | - |
dc.subject.local | Interleukin-6 (IL-6) | - |
dc.subject.local | IL-6 | - |
dc.subject.local | Il-6 | - |
dc.subject.local | interleukin-6 | - |
dc.subject.local | interleukin-6 (IL-6) | - |
dc.subject.local | Interleukin-6 | - |
dc.subject.local | Signal transducer and activator of transcription 3 (STAT3) | - |
dc.subject.local | Signal transducer and activator of transcription | - |
dc.subject.local | Signal transducer and activator of transcription 3 (Stat3) | - |
dc.subject.local | STAT 3 | - |
dc.subject.local | STAT3 | - |
dc.subject.local | Signal transducer and activator of transcription 3 | - |
dc.subject.local | Stat3 | - |
dc.subject.local | Signal transducer and activator of transcription factor 3 (STAT3) | - |
dc.subject.local | inflammation | - |
dc.subject.local | Inflammation | - |
dc.description.journalClass | Y | - |
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