Sesquiterpenoids from the rhizomes of Curcuma phaeocaulis and their inhibitory effects on LPS-induced TLR4 activation = 아출로부터 분리된 세스퀴테르페노이드 화합물의 TLR-4 저해활성

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dc.contributor.authorHyun Jae Jang-
dc.contributor.authorJin Han Kim-
dc.contributor.authorHyun-Mee Oh-
dc.contributor.authorMin Suk Kim-
dc.contributor.authorJin Ha Jo-
dc.contributor.authorKyungsook Jung-
dc.contributor.authorSoyoung Lee-
dc.contributor.authorY H Kim-
dc.contributor.authorWoo Song Lee-
dc.contributor.authorSeung Woong Lee-
dc.contributor.authorMun Chual Rho-
dc.date.accessioned2017-04-19T10:26:28Z-
dc.date.available2017-04-19T10:26:28Z-
dc.date.issued2016-
dc.identifier.issn0009-2363-
dc.identifier.uri10.1248/cpb.c16-00086ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/13415-
dc.description.abstractTwo new guaiane-type (2, 6) and one new furanogermacrane-type (11) sesquiterpenoids have been isolated along with twelve known compounds from an EtOAc-soluble extract of Curcuma phaeocaulis rhizomes. The structures of the isolated compounds were elucidated using a combination of NMR, MS, and circular dichroism (CD) spectra. The inhibitory effects of each compound on lipopolysaccharide (LPS)-induced Toll-like receptor 4 (TLR4) activation in THP-1-Blue cells were assessed, and compound 4 showed more potent inhibitory activity against LPS-stimulated TLR4 activation.-
dc.publisherPharmaceutical Soc Japan-
dc.titleSesquiterpenoids from the rhizomes of Curcuma phaeocaulis and their inhibitory effects on LPS-induced TLR4 activation = 아출로부터 분리된 세스퀴테르페노이드 화합물의 TLR-4 저해활성-
dc.title.alternativeSesquiterpenoids from the rhizomes of Curcuma phaeocaulis and their inhibitory effects on LPS-induced TLR4 activation-
dc.typeArticle-
dc.citation.titleChemical & Pharmaceutical Bulletin-
dc.citation.number7-
dc.citation.endPage1066-
dc.citation.startPage1062-
dc.citation.volume64-
dc.contributor.affiliatedAuthorHyun Jae Jang-
dc.contributor.affiliatedAuthorJin Han Kim-
dc.contributor.affiliatedAuthorHyun-Mee Oh-
dc.contributor.affiliatedAuthorMin Suk Kim-
dc.contributor.affiliatedAuthorJin Ha Jo-
dc.contributor.affiliatedAuthorKyungsook Jung-
dc.contributor.affiliatedAuthorSoyoung Lee-
dc.contributor.affiliatedAuthorWoo Song Lee-
dc.contributor.affiliatedAuthorSeung Woong Lee-
dc.contributor.affiliatedAuthorMun Chual Rho-
dc.contributor.alternativeName장현재-
dc.contributor.alternativeName김진한-
dc.contributor.alternativeName오현미-
dc.contributor.alternativeName김민석-
dc.contributor.alternativeName조진하-
dc.contributor.alternativeName정경숙-
dc.contributor.alternativeName이소영-
dc.contributor.alternativeName김영호-
dc.contributor.alternativeName이우송-
dc.contributor.alternativeName이승웅-
dc.contributor.alternativeName노문철-
dc.identifier.bibliographicCitationChemical & Pharmaceutical Bulletin, vol. 64, no. 7, pp. 1062-1066-
dc.identifier.doi10.1248/cpb.c16-00086-
dc.subject.keywordCurcuma phaeocaulis-
dc.subject.keywordLipopolysaccharide (LPS)-
dc.subject.keywordSesquiterpenoid-
dc.subject.keywordToll-like receptor 4 (TLR4)-
dc.subject.keywordZingiberaceae-
dc.subject.localCurcuma phaeocaulis-
dc.subject.locallipopolysaccharide (LPS)-
dc.subject.localLipopolysaccharide-
dc.subject.locallipopolysaccharide-
dc.subject.localLipopolysaccharide (LPS)-
dc.subject.localLipopolysaccharides-
dc.subject.localsesquiterpenoid-
dc.subject.localSesquiterpenoid-
dc.subject.localToll-like receptor 4-
dc.subject.localToll-like-receptor4-
dc.subject.localToll-like receptor 4 (TLR4)-
dc.subject.localTLR4-
dc.subject.localZingiberaceae-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
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