DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hyun Jae Jang | - |
dc.contributor.author | Jin Han Kim | - |
dc.contributor.author | Hyun-Mee Oh | - |
dc.contributor.author | Min Suk Kim | - |
dc.contributor.author | Jin Ha Jo | - |
dc.contributor.author | Kyungsook Jung | - |
dc.contributor.author | Soyoung Lee | - |
dc.contributor.author | Y H Kim | - |
dc.contributor.author | Woo Song Lee | - |
dc.contributor.author | Seung Woong Lee | - |
dc.contributor.author | Mun Chual Rho | - |
dc.date.accessioned | 2017-04-19T10:26:28Z | - |
dc.date.available | 2017-04-19T10:26:28Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0009-2363 | - |
dc.identifier.uri | 10.1248/cpb.c16-00086 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/13415 | - |
dc.description.abstract | Two new guaiane-type (2, 6) and one new furanogermacrane-type (11) sesquiterpenoids have been isolated along with twelve known compounds from an EtOAc-soluble extract of Curcuma phaeocaulis rhizomes. The structures of the isolated compounds were elucidated using a combination of NMR, MS, and circular dichroism (CD) spectra. The inhibitory effects of each compound on lipopolysaccharide (LPS)-induced Toll-like receptor 4 (TLR4) activation in THP-1-Blue cells were assessed, and compound 4 showed more potent inhibitory activity against LPS-stimulated TLR4 activation. | - |
dc.publisher | Pharmaceutical Soc Japan | - |
dc.title | Sesquiterpenoids from the rhizomes of Curcuma phaeocaulis and their inhibitory effects on LPS-induced TLR4 activation = 아출로부터 분리된 세스퀴테르페노이드 화합물의 TLR-4 저해활성 | - |
dc.title.alternative | Sesquiterpenoids from the rhizomes of Curcuma phaeocaulis and their inhibitory effects on LPS-induced TLR4 activation | - |
dc.type | Article | - |
dc.citation.title | Chemical & Pharmaceutical Bulletin | - |
dc.citation.number | 7 | - |
dc.citation.endPage | 1066 | - |
dc.citation.startPage | 1062 | - |
dc.citation.volume | 64 | - |
dc.contributor.affiliatedAuthor | Hyun Jae Jang | - |
dc.contributor.affiliatedAuthor | Jin Han Kim | - |
dc.contributor.affiliatedAuthor | Hyun-Mee Oh | - |
dc.contributor.affiliatedAuthor | Min Suk Kim | - |
dc.contributor.affiliatedAuthor | Jin Ha Jo | - |
dc.contributor.affiliatedAuthor | Kyungsook Jung | - |
dc.contributor.affiliatedAuthor | Soyoung Lee | - |
dc.contributor.affiliatedAuthor | Woo Song Lee | - |
dc.contributor.affiliatedAuthor | Seung Woong Lee | - |
dc.contributor.affiliatedAuthor | Mun Chual Rho | - |
dc.contributor.alternativeName | 장현재 | - |
dc.contributor.alternativeName | 김진한 | - |
dc.contributor.alternativeName | 오현미 | - |
dc.contributor.alternativeName | 김민석 | - |
dc.contributor.alternativeName | 조진하 | - |
dc.contributor.alternativeName | 정경숙 | - |
dc.contributor.alternativeName | 이소영 | - |
dc.contributor.alternativeName | 김영호 | - |
dc.contributor.alternativeName | 이우송 | - |
dc.contributor.alternativeName | 이승웅 | - |
dc.contributor.alternativeName | 노문철 | - |
dc.identifier.bibliographicCitation | Chemical & Pharmaceutical Bulletin, vol. 64, no. 7, pp. 1062-1066 | - |
dc.identifier.doi | 10.1248/cpb.c16-00086 | - |
dc.subject.keyword | Curcuma phaeocaulis | - |
dc.subject.keyword | Lipopolysaccharide (LPS) | - |
dc.subject.keyword | Sesquiterpenoid | - |
dc.subject.keyword | Toll-like receptor 4 (TLR4) | - |
dc.subject.keyword | Zingiberaceae | - |
dc.subject.local | Curcuma phaeocaulis | - |
dc.subject.local | lipopolysaccharide (LPS) | - |
dc.subject.local | Lipopolysaccharide | - |
dc.subject.local | lipopolysaccharide | - |
dc.subject.local | Lipopolysaccharide (LPS) | - |
dc.subject.local | Lipopolysaccharides | - |
dc.subject.local | sesquiterpenoid | - |
dc.subject.local | Sesquiterpenoid | - |
dc.subject.local | Toll-like receptor 4 | - |
dc.subject.local | Toll-like-receptor4 | - |
dc.subject.local | Toll-like receptor 4 (TLR4) | - |
dc.subject.local | TLR4 | - |
dc.subject.local | Zingiberaceae | - |
dc.description.journalClass | Y | - |
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