Facile and sensitive detection of influenza viruses using SERS antibody probes

Cited 14 time in scopus
Metadata Downloads
Title
Facile and sensitive detection of influenza viruses using SERS antibody probes
Author(s)
Jeong Moon; So Yeon Yi; Ahreum Hwang; Gayoung Eom; Jieun Sim; Jinyoung JeongEun Kyung Lim; Bong Hyun Chung; B Kim; Juyeon JungTaejoon Kang
Bibliographic Citation
Rsc Advances, vol. 6, no. 87, pp. 84415-84419
Publication Year
2016
Abstract
It is highly important to identify influenza viruses rapidly and accurately for the prevention of future pandemic outbreaks. We developed an easy and sensitive influenza virus detection method using surface-enhanced Raman scattering (SERS) antibody probes. The SERS antibody probes can be prepared easily by mixing Au nanoparticles, gold binding peptide-protein G, and antibodies without complicated chemical or biological reactions. They also retain the optimal conformation for the antibody's interaction with Influenza A/CA/07/2009 (pH1N1), allowing us to detect pH1N1 sensitively and selectively. This method provides a detection limit of 4.1 × 103 TCID per mL and is highly selective for pH1N1. We anticipate that this method can be useful in a wide range of immunoassays.
ISSN
2046-2069
Publisher
Royal Soc Chem
DOI
http://dx.doi.org/10.1039/c6ra13966c
Type
Article
Appears in Collections:
Division of Research on National Challenges > Environmental diseases research center > 1. Journal Articles
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.