DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bong Hyun Sung | - |
dc.contributor.author | D CHoe | - |
dc.contributor.author | S C Kim | - |
dc.contributor.author | B K Cho | - |
dc.date.accessioned | 2017-04-19T10:31:24Z | - |
dc.date.available | 2017-04-19T10:31:24Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0071-1365 | - |
dc.identifier.uri | 10.1042/EBC20160024 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/13645 | - |
dc.description.abstract | Microbibal diversity and complexity pose challenges in understanding the voluminous genetic information produced from whole-genome sequences, bioinrofmatics and high-throughput'-omics' research. These challenges can be overcome by a core blueprint of a genome drawn with a minimal gene set, which is essential for life. Systems biologt and large-scale gene inactivation studies have estimated the number of essential genes to be ~300-500 in mant microbial genomes. On the basis of the essential gene set information, minimal-genime strains have been generated using sophisticated geno,e engineering techniques, such as genome reduction and chemocal genome synthesized genomes have just been con-structed. Some minimal genomes provide various desirable functions for bioindustry, such as improved genome stabilaty, increased transformation efficacy and improved production of biomaterials. The minimal genome as a chassis geno,e for synthetic biology can be used to construct custom-designed genomes for various practical and industrial applications. | - |
dc.publisher | Portland Press Ltd | - |
dc.title | Construction of a minimal genome as a chassis for synthetic biology = 합성생물학을 위한 뼈대로써 최소 유전체 제작 | - |
dc.title.alternative | Construction of a minimal genome as a chassis for synthetic biology | - |
dc.type | Article | - |
dc.citation.title | Essays in Biochemistry | - |
dc.citation.number | 4 | - |
dc.citation.endPage | 346 | - |
dc.citation.startPage | 337 | - |
dc.citation.volume | 60 | - |
dc.contributor.affiliatedAuthor | Bong Hyun Sung | - |
dc.contributor.alternativeName | 성봉현 | - |
dc.contributor.alternativeName | 최동희 | - |
dc.contributor.alternativeName | 김선창 | - |
dc.contributor.alternativeName | 조병관 | - |
dc.identifier.bibliographicCitation | Essays in Biochemistry, vol. 60, no. 4, pp. 337-346 | - |
dc.identifier.doi | 10.1042/EBC20160024 | - |
dc.description.journalClass | Y | - |
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