Cited 5 time in
- Title
- Gain switching for a detection system to accommodate a newly developed MALDI-based quantification method
- Author(s)
- S H Ahn; T Hyeon; M S Kim; Jeong Hee Moon
- Bibliographic Citation
- Journal of American Society for Mass Spectrometry, vol. 28, no. 9, pp. 1987-1990
- Publication Year
- 2017
- Abstract
- In matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF), matrix-derived ions are routinely deflected away to avoid problems with ion detection. This, however, limits the use of a quantification method that utilizes the analyte-to-matrix ion abundance ratio. In this work, we will show that it is possible to measure this ratio by a minor instrumental modification of a simple form of MALDI-TOF. This involves detector gain switching. [Figure not available: see fulltext.].
- Keyword
- Detector gain switchingMALDI quantificationMALDI-TOF instrument
- ISSN
- 1044-0305
- Publisher
- Amer Soc Mass Spectr
- DOI
- http://dx.doi.org/10.1007/s13361-017-1711-2
- Type
- Article
- Appears in Collections:
- Division of Bio Technology Innovation > Core Research Facility & Analysis Center > 1. Journal Articles
- Files in This Item:
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