Open Access@KRIBBSynthetic Biology and Bioengineering Research InstituteGenome Editing Research Center1. Journal Articles
Stably fluorescent cell line of human ovarian epithelial cancer cells SK-OV-3ip-red
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- Title
- Stably fluorescent cell line of human ovarian epithelial cancer cells SK-OV-3ip-red
- Author(s)
- E V Konovalova; A A Shulga; S P Chumakov; Y M Khodarovich; Eui-Jeon Woo; S M Deev
- Bibliographic Citation
- Bulletin of Experimental Biology and Medicine, vol. 164, no. 1, pp. 99-101
- Publication Year
- 2017
- Abstract
- Stable red fluorescing line of human ovarian epithelial cancer cells SK-OV-3ip-red was generated expressing gene coding for protein TurboFP635 (Katushka) fluorescing in the far-red spectrum region with excitation and emission peaks at 588 and 635 nm, respectively. Fluorescence of SK-OV-3ip-red line remained high during long-term cell culturing and after cryogenic freezing. The obtained cell line SK-OV-3ip-red can serve a basis for a model of a scattered tumor with numerous/extended metastases and used both for testing anticancer drugs inhibiting metastasis growth and for non-invasive monitoring of the growth dynamics with high precision.
- ISSN
- 0007-4888
- Publisher
- Springer
- Full Text Link
- http://dx.doi.org/10.1007/s10517-017-3933-5
- Type
- Article
- Appears in Collections:
- Synthetic Biology and Bioengineering Research Institute > Genome Editing Research Center > 1. Journal Articles
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