Biological control of Flavobacterium psychrophilum infection in ayu (Plecoglossus altivelis altivelis) using a bacteriophage PFpW-3

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Title
Biological control of Flavobacterium psychrophilum infection in ayu (Plecoglossus altivelis altivelis) using a bacteriophage PFpW-3
Author(s)
Ji Hyung Kim; S C Park
Bibliographic Citation
Korean Journal of Veterinary Research, vol. 58, no. 1, pp. 39-43
Publication Year
2018
Abstract
The efficacy of using a bacteriophage (phage) to control Flavobacterium psychrophilum (F. psychrophilum) infection of ayu (Plecoglossus altivelis altivelis) was evaluated in this study. Intramuscular challenge failed to induce sufficient infection levels; therefore, a newly designed net-scratch challenge method was also used to induce bacterial infection. Administration of phage PFpW-3 in F. psychrophilum-infected ayu showed notable protective effects, increased survival rates and mean times to death. Additionally, the fate of inoculated bacteria and phage in ayu were investigated. Our results suggest that the phage PFpW-3 could be considered an alternative biocontrol agent against F. psychrophilum infections in ayu culture
Keyword
AyuBacteriophagesFlavobacterium psychrophilumPFpW-3
ISSN
1225-0198
Publisher
Korea Soc-Assoc-Inst
DOI
http://dx.doi.org/10.14405/kjvr.2018.58.1.39
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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