Immunomodulatory effects of β-1,3/1,6-glucan and lactic acid bacteria in LP-BM5 murine leukemia viruses-induced murine acquired immune deficiency syndrome = 면역결핍 모델에서 β-1,3/1,6-glucan과 유산균을 이용한 in vivo 면역 활성 조절 효과

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dc.contributor.authorMinsoo Kim-
dc.contributor.authorJoong Su Kim-
dc.contributor.authorM J Ryu-
dc.contributor.authorK H Kim-
dc.contributor.authorK Hwang-
dc.date.accessioned2018-07-19T16:30:07Z-
dc.date.available2018-07-19T16:30:07Z-
dc.date.issued2017-
dc.identifier.issnI000-0178-
dc.identifier.uri10.11002/kjfp.2017.24.8.1158ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/17823-
dc.description.abstractIn this study, β-1,3/1,6-glucan, lactic acid bacteria, and β-1,3/1,6-glucan+lactic acid bacteria were tested for 10 weeks using an immunodeficient animal model infected with LP-BM5 murine AIDS virus On the immune activity. Cytokines production, plasma immunoglobulin concentration, T cell and B cell proliferation were measured. As a result, the T cell proliferative capacity which was weakened by immunization with LP-BM5 murine AIDS virus increased significantly T cell proliferative capacity compared with the red ginseng control group. B cell proliferative capacity was significantly higher than the infected control group. Increased B cell proliferation was reduced. In the cytokine production, IL-2, IL-12 and IL-15 in the Th1-type cytokine increased the secretion of IL-2, IL-12 and IL-15 compared to the infected control. The proliferative capacity of the treated group was higher than that of the mixed treatment group. TNF-a was significantly decreased compared with the infected control group. The IL-4, IL-6 and IL-10 levels were significantly inhibited in the infected control group and the Th1/Th2 type cytokine expression was regulated by immunohistochemistry. IgE, IgA, and IgG levels were significantly lower in the immunoglobulin secretion assay than in the control. As a result, the immunomodulatory effect of β-1,3/1,6-glucan+lactic acid bacteria was confirmed by mixing with LP-BM5 murine AIDS virus-infected immunodeficient animal model-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleImmunomodulatory effects of β-1,3/1,6-glucan and lactic acid bacteria in LP-BM5 murine leukemia viruses-induced murine acquired immune deficiency syndrome = 면역결핍 모델에서 β-1,3/1,6-glucan과 유산균을 이용한 in vivo 면역 활성 조절 효과-
dc.title.alternativeImmunomodulatory effects of β-1,3/1,6-glucan and lactic acid bacteria in LP-BM5 murine leukemia viruses-induced murine acquired immune deficiency syndrome-
dc.typeArticle-
dc.citation.titleKorean Journal of Food Preservation-
dc.citation.number8-
dc.citation.endPage1167-
dc.citation.startPage1158-
dc.citation.volume24-
dc.contributor.affiliatedAuthorMinsoo Kim-
dc.contributor.affiliatedAuthorJoong Su Kim-
dc.contributor.alternativeName김민수-
dc.contributor.alternativeName김중수-
dc.contributor.alternativeName류민정-
dc.contributor.alternativeName김기홍-
dc.contributor.alternativeName황권택-
dc.identifier.bibliographicCitationKorean Journal of Food Preservation, vol. 24, no. 8, pp. 1158-1167-
dc.identifier.doi10.11002/kjfp.2017.24.8.1158-
dc.subject.keywordB-1,3/1,6-glucan-
dc.subject.keywordCytokines-
dc.subject.keywordImmunomodulatory effect-
dc.subject.keywordIn vivo-
dc.subject.keywordLactic acid bacteria-
dc.subject.localB-1,3/1,6-glucan-
dc.subject.localCytokine-
dc.subject.localCytokines-
dc.subject.localcytokine-
dc.subject.localImmunomodulatory effect-
dc.subject.localIn vivo-
dc.subject.localin vivo-
dc.subject.localLactic acid bacteria-
dc.subject.locallactic acid bacteria-
dc.subject.locallacti acid bateria-
dc.description.journalClassN-
Appears in Collections:
Jeonbuk Branch Institute > Microbial Biotechnology Research Center > 1. Journal Articles
Division of Bio Technology Innovation > SME Support Center > 1. Journal Articles
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