Four new flavonoids with DGAT inhibitory activity from Psoralea corylifolia
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | H Z Li | - |
| dc.contributor.author | X Meng | - |
| dc.contributor.author | Y Y Jiang | - |
| dc.contributor.author | X Lin | - |
| dc.contributor.author | D X Xiong | - |
| dc.contributor.author | D Wang | - |
| dc.contributor.author | Hyun Sun Lee | - |
| dc.contributor.author | L Cui | - |
| dc.date.accessioned | 2019-01-23T16:30:24Z | - |
| dc.date.available | 2019-01-23T16:30:24Z | - |
| dc.date.issued | 2018 | - |
| dc.identifier.issn | 1874-3900 | - |
| dc.identifier.uri | 10.1016/j.phytol.2018.10.005 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/18152 | - |
| dc.description.abstract | Four new compounds, 3′'-methoxy-bavacoumestan C (1), 6,7-furanbavachinone B (2), 3,4- furanbavachalcone A (3) and 4,5- furanbavachalcone A (4), together with seven known flavonoids were isolated from the Psoralea corylifolia. Their structures were determined by extensive spectroscopic and physicochemical analyses. All the compounds (1？11) were evaluated for in vitro inhibitory activity against DGAT. Among them, compounds 1, 6, 7, 10 and 11 were found to exhibit selective inhibitory activity on DGAT1with IC50 values ranging from 78.5 ± 1.7 to 153.4 ± 1.5 μM. | - |
| dc.publisher | Elsevier | - |
| dc.title | Four new flavonoids with DGAT inhibitory activity from Psoralea corylifolia | - |
| dc.title.alternative | Four new flavonoids with DGAT inhibitory activity from Psoralea corylifolia | - |
| dc.type | Article | - |
| dc.citation.title | Phytochemistry Letters | - |
| dc.citation.number | 0 | - |
| dc.citation.endPage | 134 | - |
| dc.citation.startPage | 130 | - |
| dc.citation.volume | 28 | - |
| dc.contributor.affiliatedAuthor | Hyun Sun Lee | - |
| dc.contributor.alternativeName | Li | - |
| dc.contributor.alternativeName | Meng | - |
| dc.contributor.alternativeName | Jiang | - |
| dc.contributor.alternativeName | Lin | - |
| dc.contributor.alternativeName | Xiong | - |
| dc.contributor.alternativeName | Wang | - |
| dc.contributor.alternativeName | 이현선 | - |
| dc.contributor.alternativeName | Cui | - |
| dc.identifier.bibliographicCitation | Phytochemistry Letters, vol. 28, pp. 130-134 | - |
| dc.identifier.doi | 10.1016/j.phytol.2018.10.005 | - |
| dc.subject.keyword | DGAT | - |
| dc.subject.keyword | Obesity | - |
| dc.subject.keyword | Psoralea corylifolia | - |
| dc.subject.local | DGAT | - |
| dc.subject.local | Obesity | - |
| dc.subject.local | obesity | - |
| dc.subject.local | Psoralea corylifolia L. | - |
| dc.subject.local | Psoralea corylifolia | - |
| dc.description.journalClass | Y | - |
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- Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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