Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Bo Yeon Kim | - |
| dc.contributor.author | Ji Hee Yoon | - |
| dc.contributor.author | M Kim | - |
| dc.contributor.author | J N Kim | - |
| dc.contributor.author | H Park | - |
| dc.contributor.author | S E Ryu | - |
| dc.contributor.author | Sangku Lee | - |
| dc.date.accessioned | 2019-07-10T01:23:30Z | - |
| dc.date.available | 2019-07-10T01:23:30Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | 10.1016/j.bmcl.2019.05.021 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/18796 | - |
| dc.description.abstract | Structure based virtual screening attempts to discover DUSP1 inhibitors have yielded a scaffold featuring benzoxazole and acylthiourea pharmacophore. A series of its analogues were synthesized to explore structure activity relationship (SAR) of DUSP1 inhibition. | - |
| dc.publisher | Elsevier | - |
| dc.title | Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition | - |
| dc.title.alternative | Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition | - |
| dc.type | Article | - |
| dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
| dc.citation.number | 14 | - |
| dc.citation.endPage | 1748 | - |
| dc.citation.startPage | 1746 | - |
| dc.citation.volume | 29 | - |
| dc.contributor.affiliatedAuthor | Bo Yeon Kim | - |
| dc.contributor.affiliatedAuthor | Ji Hee Yoon | - |
| dc.contributor.affiliatedAuthor | Sangku Lee | - |
| dc.contributor.alternativeName | 김보연 | - |
| dc.contributor.alternativeName | 윤지희 | - |
| dc.contributor.alternativeName | 김명빈 | - |
| dc.contributor.alternativeName | 김재녕 | - |
| dc.contributor.alternativeName | 박황서 | - |
| dc.contributor.alternativeName | 류성언 | - |
| dc.contributor.alternativeName | 이상구 | - |
| dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 29, no. 14, pp. 1746-1748 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2019.05.021 | - |
| dc.subject.keyword | Dual specificity phosphatase | - |
| dc.subject.keyword | Mitogen-activated protein kinase | - |
| dc.subject.keyword | Enzyme inhibition | - |
| dc.subject.keyword | Structure activity relationship | - |
| dc.subject.keyword | Cancer | - |
| dc.subject.local | Dual specificity phosphatase | - |
| dc.subject.local | mitogen-activated protein kinase | - |
| dc.subject.local | Mitogen activated protein kinase | - |
| dc.subject.local | Mitogen-activated protein (MAP) kinase | - |
| dc.subject.local | mitogen-activated protein kinases | - |
| dc.subject.local | Mitogen-activated protein kinase (MAPK) | - |
| dc.subject.local | Mitogen-activated protein kinase | - |
| dc.subject.local | Mitogenactivated protein kinase | - |
| dc.subject.local | mitogen activated protein kinase | - |
| dc.subject.local | Mitogen-activated protein kinases (MAPKs) | - |
| dc.subject.local | Mitogen-acti-vated protein kinase | - |
| dc.subject.local | Mitogen-activated protein kinases | - |
| dc.subject.local | enzyme inhibition | - |
| dc.subject.local | Enzyme inhibition | - |
| dc.subject.local | Structure activity relationship | - |
| dc.subject.local | structure activity relationship | - |
| dc.subject.local | Cancers | - |
| dc.subject.local | cancer | - |
| dc.subject.local | Cancer | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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