Wild nutria (Myocastor coypus) is a potential reservoir of carbapenem-resistant and zoonotic Aeromonas spp. in Korea

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Title
Wild nutria (Myocastor coypus) is a potential reservoir of carbapenem-resistant and zoonotic Aeromonas spp. in Korea
Author(s)
Se Ra Lim; D H Lee; Seon Young Park; S Lee; Hyo Yeon Kim; Moo-Seung Lee; J R Lee; J E Han; H K Kim; Ji Hyung Kim
Bibliographic Citation
Microorganisms, vol. 7, no. 8, pp. 224-224
Publication Year
2019
Abstract
The emergence and spread of antibiotic-resistant Aeromonas spp. is a serious public and animal health concern. Wild animals serve as reservoirs, vectors, and sentinels of these bacteria and can facilitate their transmission to humans and livestock. The nutria (Myocastor coypus), a semi-aquatic rodent, currently is globally considered an invasive alien species that has harmful impacts on natural ecosystems and carries various zoonotic aquatic pathogens. This study aimed to determine the prevalence of antibiotic-resistant zoonotic Aeromonas spp. in wild invasive nutrias captured in Korea during governmental eradication program. Three potential zoonotic Aeromonas spp. (A. hydrophila, A. caviae, and A. dhakensis) were identified among isolates from nutria. Some strains showed unexpected resistance to fluoroquinolones, third-generation cephalosporins, and carbapenems. In carbapenem-resistant isolates, the cphA gene, which is related to intrinsic resistance of Aeromonas to carbapenems, was identified, and phylogenetic analysis based on this gene revealed the presence of two major groups represented by A. hydrophila (including A. dhakensis) and other Aeromonas spp. These results indicate that wild nutrias in Korea are a potential reservoir of zoonotic and antibiotic-resistant Aeromonas spp. that can cause infection and treatment failure in humans. Thus, measures to prevent contact of wild nutrias with livestock and humans are needed.
Keyword
Aeromonas spp.antibiotic resistancecarbapenemcphAnutria (Myocastor coypus)
ISSN
2076-2607
Publisher
MDPI
DOI
http://dx.doi.org/10.3390/microorganisms7080224
Type
Article
Appears in Collections:
Division of Research on National Challenges > Environmental diseases research center > 1. Journal Articles
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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