Anti-inflammatory secondary metabolites from the stems of Millettia dielsiana Harms ex Diels

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Title
Anti-inflammatory secondary metabolites from the stems of Millettia dielsiana Harms ex Diels
Author(s)
L D Dat; N T M Tu; N V Duc; B T T Luyen; C T T Huyen; Hyun Jae Jang; D T Thu; T T Huong; L H Tram; N V Thong; N D Hung; Y H Kim; N P Thao
Bibliographic Citation
Carbohydrate Research, vol. 484, pp. 107778-107778
Publication Year
2019
Abstract
A phytochemical investigation for the constituents of the stems of Millettia dielsiana Harms ex Diels resulted in the isolation of a new isoflavone glycoside, mildiside A (1), and 14 known compounds (2?15). Their chemical structures were determined using a combination of IR, NMR, MS, and optical rotation analysis, as well as comparison with the literature data. The ethanolic (EtOH) extract and several isolated compounds exert the inflammatory effect of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cells.
Keyword
Anti-inflammatory effectLeguminosaeMildiside AMillettia dielsianaPhenolic compound
ISSN
0008-6215
Publisher
Elsevier
Full Text Link
http://dx.doi.org/10.1016/j.carres.2019.107778
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
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