Xanthones from the stems of Cudrania tricuspidata and their inhibitory effects on pancreatic lipase and fat accumulation

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dc.contributor.authorY H Jo-
dc.contributor.authorS B Kim-
dc.contributor.authorJ H Ahn-
dc.contributor.authorA Turk-
dc.contributor.authorEun-Bin Kwon-
dc.contributor.authorMun-Ock Kim-
dc.contributor.authorB Y Hwang-
dc.contributor.authorM K Lee-
dc.date.accessioned2019-10-28T16:30:29Z-
dc.date.available2019-10-28T16:30:29Z-
dc.date.issued2019-
dc.identifier.issn0045-2068-
dc.identifier.uri10.1016/j.bioorg.2019.103234ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/18957-
dc.description.abstractNine new xanthones, cudracuspixanthones I - Q (12-14, 25, 32-36), and 30 known xanthones (1-11, 15-24, 26-31, 37-39) were isolated from the stems of Cudrania tricuspidata (Moraceae). The structures of isolated compounds were established by using 1D and 2D NMR in combination with HR-TOF-MS. Xanthones from the stems of C. tricuspidata exerted pancreatic lipase inhibitory activity. In addition, cudracuspixanthone P (35), a new xanthone, reduced the fat accumulation in liver cells stimulated with fatty acids. Therefore, these compounds might be beneficial in the treatment of metabolic diseases.-
dc.publisherElsevier-
dc.titleXanthones from the stems of Cudrania tricuspidata and their inhibitory effects on pancreatic lipase and fat accumulation-
dc.title.alternativeXanthones from the stems of Cudrania tricuspidata and their inhibitory effects on pancreatic lipase and fat accumulation-
dc.typeArticle-
dc.citation.titleBioorganic Chemistry-
dc.citation.number0-
dc.citation.endPage103234-
dc.citation.startPage103234-
dc.citation.volume92-
dc.contributor.affiliatedAuthorEun-Bin Kwon-
dc.contributor.affiliatedAuthorMun-Ock Kim-
dc.contributor.alternativeName조양희-
dc.contributor.alternativeName김선범-
dc.contributor.alternativeName안종훈-
dc.contributor.alternativeNameTurk-
dc.contributor.alternativeName권은빈-
dc.contributor.alternativeName김문옥-
dc.contributor.alternativeName황방연-
dc.contributor.alternativeName이미경-
dc.identifier.bibliographicCitationBioorganic Chemistry, vol. 92, pp. 103234-103234-
dc.identifier.doi10.1016/j.bioorg.2019.103234-
dc.subject.keywordCudracuspixanthones I - Q-
dc.subject.keywordCudrania tricuspidata-
dc.subject.keywordFat accumulation-
dc.subject.keywordMoraceae-
dc.subject.keywordPancreatic lipase-
dc.subject.localCudracuspixanthones I - Q-
dc.subject.localcudrania tricuspidata-
dc.subject.localCudrania tricuspidata-
dc.subject.localFat accumulation-
dc.subject.localmoraceae-
dc.subject.localMoraceae-
dc.subject.localPancreatic lipase-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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