Development of systems for the production of plant-derived biopharmaceuticals

Cited 48 time in scopus
Metadata Downloads
Development of systems for the production of plant-derived biopharmaceuticals
Ki-Beom Moon; Ji-Sun Park; Y I Park; In Ja SongHyo Jun LeeHye Sun Cho; Jae Heung Jeon; Hyun Soon Kim
Bibliographic Citation
Plants-Basel, vol. 9, pp. 30-30
Publication Year
Over the last several decades, plants have been developed as a platform for the production of useful recombinant proteins due to a number of advantages, including rapid production and scalability, the ability to produce unique glycoforms, and the intrinsic safety of food crops. The expression methods used to produce target proteins are divided into stable and transient systems depending on applications that use whole plants or minimally processed forms. In the early stages of research, stable expression systems were mostly used; however, in recent years, transient expression systems have been preferred. The production of the plant itself, which produces recombinant proteins, is currently divided into two major approaches, open-field cultivation and closed-indoor systems. The latter encompasses such regimes as greenhouses, vertical farming units, cell bioreactors, and hydroponic systems. Various aspects of each system will be discussed in this review, which focuses mainly on practical examples and commercially feasible approaches.
expression systemmolecular farmingplant-derived proteinproduction systemrecombinant protein
Appears in Collections:
National Research Safety Headquarter > 1. Journal Articles
Division of Research on National Challenges > Plant Systems Engineering Research > 1. Journal Articles
Files in This Item:

Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.