Identification and genome analysis of Vibrio coralliilyticus causing mortality of Pacific oyster (Crassostrea gigas) larvae

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dc.contributor.authorH J Kim-
dc.contributor.authorJ W Jun-
dc.contributor.authorS S Giri-
dc.contributor.authorC Chi-
dc.contributor.authorS Yun-
dc.contributor.authorS G Kim-
dc.contributor.authorS W Kim-
dc.contributor.authorS J Han-
dc.contributor.authorJ Kwon-
dc.contributor.authorO T Oh-
dc.contributor.authorS B Lee-
dc.contributor.authorJi Hyung Kim-
dc.contributor.authorS C Park-
dc.date.accessioned2020-04-24T16:30:28Z-
dc.date.available2020-04-24T16:30:28Z-
dc.date.issued2020-
dc.identifier.issn20760817-
dc.identifier.uri10.3390/pathogens9030206ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/19409-
dc.description.abstractVibrio coralliilyticus is known as a coral pathogen that also infects marine bivalve larvae worldwide. It is considered to be one of the major constraints in artificial marine bivalve seed production as it causes mortality. In this study, we first isolated and characterized a high virulent of V. coralliilyticus designated as SNUTY-1 that was the cause of Pacific oyster larvae mortality in Korea. In the pathogenicity test, exposure to 2.14 × 105 CFU/mL for 24 h caused mortality to 88.65 ± 2.4% of the tested healthy Pacific oyster larvae. SNUTY-1 showed anti-microbial resistance to β-lactams, such as penicillins, cephalosporins, and carbapenems. We sequenced and assembled the complete genome of SNUTY-1 (5,842,676 bp), consisting of two chromosomes (Chr I and Chr II) and two plasmids (pSNUTY1 and pSNUTY2). The COG functional analysis confirmed that Chr I had more genes associated with basic cellular functions in comparison to Chr II. The results of the phylogenetic trees based on OrthoANI values indicated that the SNUTY-1 was closely related to V. coralliilyticus strains. SNUTY-1 had a unique plasmid (pSNUTY2), which could mean that the Korean isolate is different from other sequenced V. coralliilyticus strains from different geographical origins. Toxic proteins such as cytolysin/hemolysin and extracellular metalloprotease genes were encoded on Chr I and Chr II of SNUTY-1. These data facilitate the control of V. coralliilyticus infections in aquaculture by providing valuable insights into the biodiversity of this organism and valuable information for the study of virulence factors.-
dc.publisherMDPI-
dc.titleIdentification and genome analysis of Vibrio coralliilyticus causing mortality of Pacific oyster (Crassostrea gigas) larvae-
dc.title.alternativeIdentification and genome analysis of Vibrio coralliilyticus causing mortality of Pacific oyster (Crassostrea gigas) larvae-
dc.typeArticle-
dc.citation.titlePathogens-
dc.citation.number3-
dc.citation.endPage206-
dc.citation.startPage206-
dc.citation.volume9-
dc.contributor.affiliatedAuthorJi Hyung Kim-
dc.contributor.alternativeName김현중-
dc.contributor.alternativeName전진우-
dc.contributor.alternativeNameGiri-
dc.contributor.alternativeNameChi-
dc.contributor.alternativeName윤새길-
dc.contributor.alternativeName김상근-
dc.contributor.alternativeName김상화-
dc.contributor.alternativeName한세진-
dc.contributor.alternativeName권준-
dc.contributor.alternativeName오우택-
dc.contributor.alternativeName이성빈-
dc.contributor.alternativeName김지형-
dc.contributor.alternativeName박세창-
dc.identifier.bibliographicCitationPathogens, vol. 9, no. 3, pp. 206-206-
dc.identifier.doi10.3390/pathogens9030206-
dc.subject.keywordChrI-
dc.subject.keywordChrII-
dc.subject.keywordPacific oyster (Crassostrea gigas) larvae-
dc.subject.keywordSNUTY-1-
dc.subject.keywordVibrio species-
dc.subject.keywordgenome analyses-
dc.subject.localChrI-
dc.subject.localChrII-
dc.subject.localPacific oyster (Crassostrea gigas) larvae-
dc.subject.localSNUTY-1-
dc.subject.localVibrio species-
dc.subject.localgenome analyses-
dc.subject.localgenome analysis-
dc.description.journalClassY-
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Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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