Division of Research on National Challenges (국가아젠다연구부)4050

Showing results 1 to 20 of 93

No. Year Title Type
1 2024

2024Article

Deficiency of thioredoxin-interacting protein (TXNIP) results in age-related thrombocytopenia due to megakaryocyte oxidative stressJournal of Thrombosis and Haemostasis, vol. 22, no. 3, pp. 834-850Eunju Shin; C Park; Taeho Park; Hyunmin Chung; H Hwang; Sung Ho Bak; Kyung-Sook ChungSuk Ran YoonTae-Don Kim; In Pyo Choi, et al.
Article
2 2023

2023Article

Efficient and reproducible generation of human induced pluripotent stem cell-derived expandable liver organoids for disease modelingScientific Reports, vol. 13, pp. 22935-22935Seon Ju Mun; Yeon Hwa Hong; Yongbo Shin; Jaeseo Lee; Hyun-Soo ChoDae Soo KimKyung-Sook ChungMyung Jin Son
Article
3 2023

2023Article

In vitro modeling of liver fibrosis with 3D co-culture system using a novel human hepatic stellate cell lineBiotechnology and Bioengineering, vol. 120, no. 5, pp. 1241-1253Ho-Joon Lee; Seon Ju Mun; Cho-Rok JungHyun Mi Kang; Jae Eun Kwon; Jae Sung Ryu; Hyo Suk Ahn; Ok Seon KwonJiwon Ahn; K S Moon, et al.
Article
4 2022

2022Article

Generation of highly expandable intestinal spheroids composed of stem cellsInternational Journal of Stem Cells, vol. 15, no. 1, pp. 104-111Ohman Kwon; Won Dong Yu; Ye Seul Son; Kwang Bo Jung; Hana LeeMi-Young Son
Article
5 2022

2022Article

Establishment of a human induced pluripotent stem cell line, KRIBBi006-A, from peripheral blood mononuclear cells derived from a healthy male donorStem Cell Research, vol. 65, pp. 102950-102950Ok Seon Kwon; Hyeon-Jin Na; Jiwon AhnKyung-Sook Chung
Article
6 2022

2022Article

Limosilactobacillus reuteri DS0384 promotes intestinal epithelial maturation via the postbiotic effect in human intestinal organoids and infant miceGut Microbes, vol. 14, no. 1, pp. 2121580-2121580Hana Lee; Kwang Bo Jung; Ohman Kwon; Ye Seul Son; Eunho Choi; Won Dong Yu; Naeun Son; Jun Hyoung Jeon; Hana Jo; Haneol Yang, et al.
Article
7 2022

2022Article

Generation of an induced pluripotent stem cell line from human liver fibroblasts from A patient with combined hepatocellular-cholangiocarcinomaCell Journal, vol. 24, no. 3, pp. 133-139Hyo Suk Ahn; Jae Sung Ryu; Jaeseo Lee; Seon Ju Mun; Yeon Hwa Hong; Yongbo Shin; Kyung-Sook ChungMyung Jin Son
Article
8 2021

2021Article

The development of a functional human small intestinal epithelium model for drug absorptionScience Advances, vol. 7, no. 23, pp. eabh1586-eabh1586Ohman Kwon; Kwang Bo Jung; Kyeong-Ryoon Lee; Ye Seul Son; Hana Lee; Jongjin Kim; Kwangho Kim; Seop Lee; Yoo-Kyung Song; Jaeeun Jung, et al.
Article
9 2021

2021Article

Current challenges associated with the use of human induced pluripotent stem cell-derived organoids in regenerative medicineInternational Journal of Stem Cells, vol. 14, no. 1, pp. 9-20Hana LeeMi-Young Son
Article
10 2021

2021Article

Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXaStem Cell Research, vol. 57, pp. 102584-102584Yongbo Shin; Seonju Mun; Jaeseo Lee; Kyung-Sook Chung; M Kim; C K Cheon; Myung Jin Son
Article
11 2021

2021Article

Effect of microbial short-chain fatty acids on CYP3A4-mediated metabolic activation of human pluripotent stem cell-derived liver organoidsCells, vol. 10, pp. 126-126Seon Ju Mun; Jaeseo Lee; Kyung-Sook ChungMi-Young SonMyung Jin Son
Article
12 2020

2020Article

Using bioengineered fluorescence for selective in vivo and ex vivo tracking of intestinal organoids derived from human pluripotent stem cellsMethods in Molecular Biology, vol. 2126, pp. 57-71Hana LeeMi Young Son
Article
13 2020

2020Article

Long-term expansion of functional human pluripotent stem cell-derived hepatic organoidsInternational Journal of Stem Cells, vol. 13, no. 2, pp. 279-286Seon Ju Mun; Yeon-Hwa Hong; Hyo-Suk Ahn; Jae-Sung Ryu; Kyung-Sook ChungMyung Jin Son
Article
14 2020

2020Article

Optimization of 3D hydrogel microenvironment for enhanced hepatic functionality of primary human hepatocytesBiotechnology and Bioengineering, vol. 117, no. 6, pp. 1864-1876Ho-Joon Lee; Jiwon AhnCho Rok Jung; Yun-Ji Jeung; Hyun Soo ChoMyung Jin SonKyung-Sook Chung
Article
15 2020

2020Article

A new experimental model to study human drug responsesBiofabrication, vol. 12, no. 4, pp. 045029-045029Kyung Hee NohHyun Mi Kang; S J Oh; J Y Lee; Dae Hun Kim; Mijin Kim; Kyung-Sook ChungMi Young SonDae Soo KimHyun Soo Cho, et al.
Article
16 2020

2020Article

Low-dose interleukin-2 alleviates dextran sodium sulfate-induced colitis in mice by recovering intestinal integrity and inhibiting AKT-dependent pathwaysTheranostics, vol. 10, no. 11, pp. 5048-5063Hana Lee; Ye Seul Son; Mi Ok Lee; Jea Woon Ryu; Kunhyang ParkOhman Kwon; Kwang Bo Jung; Kwangho Kim; Tae Young Ryu; Areum Baek, et al.
Article
17 2020

2020Article

Iroquois homeobox protein 2 identified as a potential Biomarker for Parkinson’s diseaseInternational Journal of Molecular Sciences, vol. 21, no. 10, pp. 3455-3455Hyuna Sim; Joo-Eun Lee; H M Yoo; Sunwha Cho; Hana LeeAruem Baek; J Kim; H Seo; M N Kweon; h G Kim, et al.
Article
18 2019

2019Article

Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1Proceedings of National Academy of Sciences of United States of America, vol. 116, no. 19, pp. 9423-9432Wantae Kim; Y S Cho; X Wang; O Park; X Ma; H Kim; W Gan; E H Jho; B Cha; Yun-Ji Jeung, et al.
Article
19 2019

2019Article

Blockade of STAT3 causes severe in vitro and in vivo maturation defects in intestinal organoids derived from human embryonic stem cellsJournal of Clinical Medicine, vol. 8, no. 7, pp. 976-976Kwang Bo Jung; Ohman KwonMi Ok LeeHana Lee; Ye Seul Son; O Habib; J H Oh; Hyun Soo ChoCho Rok JungJanghwan Kim, et al.
Article
20 2019

2019Article

Targeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver modelJournal of Biological Engineering, vol. 13, pp. 69-69Jae Sung Ryu; M Lee; Seon Ju Mun; S H Hong; Ho-Joon Lee; Hyo Suk Ahn; Kyung-Sook Chung; G H Kim; Myung Jin Son
Article
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