Biotherapeutics Translational Research Center (바이오신약중개연구센터)515

연구분야

  • 암/혈관신생/혈관염증 조절 표적 발굴 및 제어 기술 개발
    • 다기능 항체 라이브러리 시스템 기반 표적 발굴 및 항체 개발
    • 줄기세포 기반 혈관내피분화조절
  • 약제내성 및 암전이 조절 규명 및 제어 기술 개발
    • 기초-임상 중개연구를 통한 신약개발
  • 암 특이적 세포대사-신호를 표적으로 한 질환 치료제 개발 및 적용기술 개발연구
    • 암세포 대사체 젖산의 역할 및 작용기전 연구
    • 젖산 신호전달체계 조절을 통한 질환 치료기술 연구
  • 면역결핍돼지 생산에 관련한 유전자 발굴
    • 면역거부반응을 일으키는 인자에 대한 메커니즘 연구
  • 질환동물 생산 및 기능적 연구
    • Gene editing system을 이용한 유전자 결손 및 변이 동물 생산
    • 동물모델을 이용한 분자유전학적 및 생리학적 기능에 대한 연구
더보기

Showing results 101 to 120 of 256

No. Year Title Type
101 2019

2019Article

The roles of hypoxia-inducible factors and non-coding RNAs in gastrointestinal cancerGenes, vol. 10, no. 12, pp. 1008-1008Hyun Soo ChoTae Su Han; K Hur; Hyun Seung Ban
Article
102 2019

2019Article

Derivation of primitive neural stem cells from human-induced pluripotent stem cellsJournal of Comparative Neurology, vol. 527, no. 18, pp. 3023-3033W J Shin; J H Seo; H W Choi; Y J Hong; W J Lee; J I Chae; S J Kim; Jeong Woong Lee; K Hong; H Song, et al.
Article
103 2019

2019Article

Thioredoxin-interacting protein promotes phagosomal acidification upon exposure to Escherichia coli through inflammasome-mediated caspase-1 activation in macrophagesFrontiers in Immunology, vol. 10, pp. 2636-2636Sung Jin Yoon; D H Jo; Seung-Ho Park; Jun-Young Park; Yoo Kyung Lee; Moo-Seung Lee; Jeong Ki Min; Haiyoung JungTae-Don KimSuk Ran Yoon, et al.
Article
104 2018

2018Article

LJ-1888, a selective antagonist for the A3 adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out miceBMB Reports, vol. 51, no. 10, pp. 520-525Jong Gil Park; S J Jeong; J Yu; G Kim; L S Jeong; G T Oh
Article
105 2018

2018Article

Pseudomonas syringae evades phagocytosis by animal cells via type III effector-mediated regulation of actin filament plasticityEnvironmental Microbiology, vol. 20, no. 11, pp. 3980-3991Sung Jin YoonYoung-Jun Park; Jun Seob Kim; Soohyun Lee; Sang Hyun Lee; Song Choi; Jeong Ki Min; In Pyo Choi; Choong-Min Ryu
Article
106 2018

2018Article

Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer = 대장암에서의 Bcl-2-의존적인 IDF-11774와 ATP6V0C 합성치사British Journal of Cancer, vol. 119, no. 11, pp. 1347-1357Bo Kyung Kim; S W Nam; B S Min; Hyun Seung Ban; S Paik; K Lee; Joo-Young Im; Youngjoo Lee; J T Park; Seon-Young Kim, et al.
Article
107 2018

2018Article

Thermotherapy for Na+/I- symporter-expressing cancer using anti-Na+/I- symporter antibody-conjugated magnetite nanoparticlesJournal of Industrial and Engineering Chemistry, vol. 63, pp. 359-365H G Jee; Hyun Seung Ban; J H Lee; S H Lee; Oh Seok Kwon; J H Choe
Article
108 2018

2018Article

Lysosomal targeting enhancement by conjugation of glycopeptides containing mannose-6-phosphate glycans derived from glyco-engineered yeastScientific Reports, vol. 8, pp. 8730-8730Ji-Yeon Kang; Keun Koo Shin; H H Kim; Jeong Ki Min; E S Ji; J Y Kim; Ohsuk KwonDoo-Byoung Oh
Article
109 2018

2018Article

Adipose-specific expression of mouse Rbp7 gene and its developmental and metabolic changesGene, vol. 670, pp. 38-45J Ahn; Dong-Hwan Kim; Y Suh; Jeong Woong Lee; K Lee
Article
110 2018

2018Article

Co-amplification of EBNA-1 and PyLT through dhfr-mediated gene amplification for improving foreign protein production in transient gene expression in CHO cellsApplied Microbiology and Biotechnology, vol. 102, no. 11, pp. 4729-4739Joo Hyoung Lee; Jong-Ho Park; Sun Hye Park; Sun Hong Kim; J Y Kim; Jeong Ki Min; G M Lee; Yeon-Gu Kim
Article
111 2018

2018Article

CCN3 secretion is regulated by palmitoylation via ZDHHC22Biochemical and Biophysical Research Communications, vol. 495, no. 4, pp. 2573-2578Y Kim; H Yang; Jeong Ki Min; Young-Jun Park; S H Jeong; S W Jang; S Shim
Article
112 2018

2018Article

Protein phosphatase 1B dephosphorylates Rho guanine nucleotide dissociation inhibitor 1 and suppresses cancer cell migration and invasionCancer Letters, vol. 417, pp. 141-151Hee Jun ChoJong-Tae KimSeon-Jin Lee; Yo Sep Hwang; Sang Yoon Park; Bo Yeon Kim; J Yoo; Kwan Soo Hong; Jeong Ki Min; Chul Ho Lee, et al.
Article
113 2018

2018Article

DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cellsOncogene, vol. 37, pp. 1251-1262Joo-Young ImBo Kyung Kim; Ji Young Lee; Seung Ho Park; Hyun Seung Ban; K E Jung; Mi Sun Won
Article
114 2018

2018Article

Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoidsNature Communications, vol. 9, pp. 3039-3039Kwang Bo Jung; Hana Lee; Ye Seul Son; Mi Ok Lee; Young-Dae Kim; S J Oh; Ohman Kwon; Sunwha Cho; Hyun Soo ChoDae Soo Kim, et al.
Article
115 2018

2018Article

O-carboranylalkoxy-1,3,5-triazine derivatives: synthesis, characterization, X-ray structural studies, and biological activityMolecules, vol. 23, no. 9, pp. 2194-2194G F Jin; Ban Hyun Seung; H Nakamura; J D Lee
Article
116 2018

2018Article

Ectopic overexpression of porcine Myh1 increased in slow muscle fibers and enhanced endurance exercise in transgenic miceInternational Journal of Molecular Sciences, vol. 19, no. 10, pp. 2959-2959Jin Seop Ahn; Dong-Hwan Kim; H B Park; S H Han; S Hwang; I C Cho; Jeong Woong Lee
Article
117 2018

2018Article

DSG2 is a functional cell surface marker for identification and isolation of human pluripotent stem cellsStem Cell Reports, vol. 11, pp. 115-127Jongjin Park; Y Son; Na Geum Lee; Kungmin Lee; Dong Gwang Lee; Jinhoi Song; Jaemin Lee; Seokho Kim; Min Ji Cho; Ju Hong Jang, et al.
Article
118 2018

2018Article

Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic fluxAutophagy, vol. 14, no. 1, pp. 120-133S J Jeong; S Kim; Jong Gil Park; I H Jung; Mi Ni Lee; S Jeon; H Y Kweon; Dae Yeul Yu; S H Lee; Y Jang, et al.
Article
119 2018

2018Article

Differential expression of microRNAs in recombinant Chinese hamster ovary cells treated with sodium butyrate using digital RNA countingJournal of Biotechnology, vol. 283, pp. 37-42Sung Min Lim; Sun-Hye Park; Joo Hyoung Lee; Sun Hong Kim; J Y Kim; Jeong Ki Min; G M Lee; Yeon-Gu Kim
Article
120 2018

2018Article

The epigenetic regulation of HCC metastasisInternational Journal of Molecular Sciences, vol. 19, no. 12, pp. 3978-3978Tae Su HanHyun Seung Ban; K Hur; Hyun Soo Cho
Article
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