Immunotherapy Research Center (면역치료제연구센터)589

연구분야

  • HSC 기반 유전자 NK세포치료제 개발 (PL1,2)
    • 융복합 NK세포치료 임상연구
    • CAR-NK 세포 치료제 개발
    • 단일세포 영상 기반 면역세포 효능 검증
    • 주입형 나노하이드로겔 복합체 기반 면역세포 3차원 배양기술 개발
  • 항암제 활용 맞춤형 혼합 NK세포치료제 개발 (PL3)
    • 암세포에 있어서 NK 세포의 공격에 대한 감수성을 높이는 항암제 개발
    • 줄기세포 유래 NK 세포 항암기능향상 항암제 개발
    • 간암 맞춤형 전임상을 통한 NK 세포 치료제와의 혼합치료 최적화 기술 개발
  • 생체 이미징을 이용한 전임상 동물모델에서의 면역세포치료 효능 검증
    • 이식된 세포에 대한 동물모델에서의 실시간 생체영상 추적으로 NK 세포치료 유효성 검증
    • 생체영상 치료효과 모니터링을 통한 NK, NK-항암제, NK-항체 치료에 대한 치료 유효성 검증
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Showing results 1 to 20 of 470

No. Year Title Type
1 2021

2021Article

Differential TM4SF5-mediated SIRT1 modulation and metabolic signaling in nonalcoholic steatohepatitis progressionJournal of Pathology, vol. 253, pp. 55-67J Ryu; E Kim; M K Kang; D G Song; E A Shin; H Lee; J W Jung; S H Nam; J E Kim; H J Kim, et al.
Article
2 2021

2021Article

Transforming growth factor β inhibits MUC5AC expression by Smad3/HDAC2 complex formation and NF-κB deacetylation at K310 in NCI-H292 cellsMolecules and Cells, vol. 44, no. 1, pp. 38-49Su Ui LeeMun-Ock Kim; Myung Ji Kang; Eun Sol Oh; H Ro; Ro-Woon Lee; Yu Na Song; Sunin Jung; Jae-Won LeeSoo Yun Lee, et al.
Article
3 2021

2021Article

Collapsin response mediator protein 4 enhances the radiosensitivity of colon cancer cells through calcium-mediated cell signalingOncology Reports, vol. 45, no. 4, pp. 6-6Sang Yoon Park; Jong-Tae Kim; Eun Sun Park; Yo Sep Hwang; Hyang Ran Yoon; Kyung Eun Baek; Haiyoung JungSuk Ran YoonBo Yeon KimHee Jun Cho, et al.
Article
4 2021

2021Article

TMEM52B suppression promotes cancer cell survival and invasion through modulating E-cadherin stability and EGFR activityJournal of Experimental & Clinical Cancer Research, vol. 40, no. 1, pp. 58-58Yunhee Lee; Dongjoon Ko; Junghwa Yoon; Y H Lee; Semi Kim
Article
5 2021

2021Article

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesisDevelopmental Cell, vol. 56, no. 8, pp. 1118-1130H Kim; Y S Lee; Seokmin Kim; S Jang; H Choi; J W Lee; Tae-Don Kim; V N Kim
Article
6 2021

2021Article

A new surface charge neutralizing nano-adjuvant to potentiate polymyxins in killing Mcr-1 mediated drug-resistant Escherichia coliPharmaceutics, vol. 13, no. 2, pp. 250-250H Cho; A Naskar; S Lee; Semi Kim; K S Kim
Article
7 2021

2021Article

P62-induced cancer-associated fibroblast activation via the Nrf2-ATF6 pathway promotes lung tumorigenesisCancers, vol. 13, no. 4, pp. 864-864Ji In Kang; Dong Hyun Kim; K W Sung; S M Shim; Hyunjoo Cha-MolstadNak-Kyun SoungKyung Ho LeeJoonsung HwangHee Gu Lee; Y T Kwon, et al.
Article
8 2021

2021Article

Exploration of alternative splicing events in mesenchymal stem cells from human induced pluripotent stem cellsGenes, vol. 12, no. 5, pp. 737-737Ji Eun Jeong; Binna SeolHan-Seop Kim; Jae Yun Kim; Yee Sook Cho
Article
9 2021

2021Article

Modeling sialidosis with neural precursor cells derived from patient-derived induced pluripotent stem cellsInternational Journal of Molecular Sciences, vol. 22, no. 9, pp. 4386-4386Binna Seol; Young-Dae Kim; Yee Sook Cho
Article
10 2021

2021Article

Tryptophanyl-tRNA synthetase as a potential therapeutic targetInternational Journal of Molecular Sciences, vol. 22, no. 9, pp. 4523-4523Young Ha Ahn; Se-Chan Oh; S Zhou; Tae-Don Kim
Article
11 2021

2021Article

Modified MYOMI-14 Korean herbal formulations have protective effects against cyclophosphamide-induced male infertility in miceAndrologia, vol. 53, no. 5, pp. e14025-e14025Arum Park; Yun Jeong Yang; J Jo; Suk Ran Yoon
Article
12 2020

2020Article

Inhibition of osteoclasts differentiation by CDC2-induced NFATc1 phosphorylationBone, vol. 131, pp. 115153-115153Hye-Min Kim; L He; Sangku Lee; Chanmi park; Dong Hyun Kim; Ho Jin Han; Junyeol Han; Joonsung HwangHyunjoo ChaKyung Ho Lee, et al.
Article
13 2020

2020Article

Toll-like receptors in natural killer cells and their application for immunotherapyJournal of Immunology Research, vol. 2020, pp. 2045860-2045860Ji Yoon NohSuk Ran YoonTae-Don KimIn Pyo ChoiHaiyoung Jung
Article
14 2020

2020Article

Wnt3a stimulation promotes primary ciliogenesis through beta-catenin phosphorylation-induced reorganization of centriolar satellitesCell Reports, vol. 30, pp. 1447-1462Mi-Lang Kyun; Sun Ok Kim; Hee Gu Lee; J A Hwang; Joonsung HwangNak Kyun SoungHyunjoo ChaSangku Lee; Y T Kwon; Bo Yeon Kim, et al.
Article
15 2020

2020Article

The Gata1low murine megakaryocyte-erythroid progenitor cells expand robustly and alter differentiation potentialBiochemical and Biophysical Research Communications, vol. 528, pp. 46-53Eunju Shin; Jong Gwan Jeong; Hyunmin Chung; Haiyoung Jung; C Park; Suk Ran YoonTae-Don Kim; S J Lee; Inpyo ChoiJi Yoon Noh
Article
16 2020

2020Article

Molecular mechanisms and emerging therapeutics for osteoporosisInternational Journal of Molecular Sciences, vol. 21, no. 20, pp. 7623-7623Ji Yoon Noh; Y Yang; Haiyoung Jung
Article
17 2020

2020Article

A three-dimensional hyaluronic acid-based niche enhances the therapeutic efficacy of human natural killer cell-based cancer immunotherapyBiomaterials, vol. 247, pp. 119960-119960Young Ha Ahn; L Ren; Seok Min Kim; Sang-Hwan Seo; Cho Rok Jung; Da-Seul Kim; Ji Yoon NohSoo Yun Lee; H Lee; M Y Cho, et al.
Article
18 2020

2020Article

Immunotherapy in hematologic malignancies: emerging therapies and novel approachesInternational Journal of Molecular Sciences, vol. 21, no. 21, pp. 8000-8000Ji Yoon Noh; H Seo; Jung Woon LeeHaiyoung Jung
Article
19 2020

2020Article

Cullin 3/KCTD5 promotes the ubiqutination of Rho guanine nucleotide dissociation inhibitor 1 and regulates its stabilityJournal of Microbiology and Biotechnology, vol. 30, no. 10, pp. 1488-1494Hee Jun Cho; K J Ryu; Kyoung Eun Baek; Jeewon Lim; T Kim; C Y Song; J Yoo; Hee Gu Lee
Article
20 2020

2020Article

Dysregulation of Rho GTPases in human cancersCancers, vol. 12, no. 5, pp. 1179-1179Haiyoung JungSuk Ran Yoon; Jeewon Lim; Hee Jun ChoHee Gu Lee
Article
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