Metabolic Regulation Research Center (대사제어연구센터)858

연구분야

  • 대사성 질환 조절 연구
    • 제2형 당뇨병 및 비만에서의 에너지 대사체계규명 및 제어기전 연구
    • 백색지방세포의 갈색지방세포로의 변환 관련 조절물질 발굴 및 기능연구
    • 저분자 화합물 또는 천연물 기반 대사질환 조절물질 스크리닝 및 기능연구
    • 동물모델을 이용한 대사이상 및 개선 상황에서의 주요 대사기관의 기능변화 및 신호전달 체계 분석
    • 오믹스 분석을 통한 대사기관 간 네트워크 조절인자 발굴 및 기능연구
  • 신경퇴행성 질환 대사조절연구
    • 신경세포의 기능 및 신경퇴행성 질환과 관련 대사체 연구 및 동물 모델 연구
  • 대식세포에 의한 당뇨 및 황반변성의 억제기전 연구
    • 대식세포의 대사조절 기전 연구
    • 대식세포의 감염병 억제 및 신호전달 조절 기전 규명
  • 암대사 제어 기전 연구
    • 화합물을 이용한 암대사 관련 표적분자 도출 및 기능조절 연구
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Showing results 141 to 160 of 643

No. Year Title Type
141 2016

2016Article

Histone H4 is cleaved by granzyme A during staurosporine-induced cell death in B-lymphoid Raji cellsBMB Reports, vol. 49, no. 10, pp. 560-565Phil Young Lee; Byoung Chul ParkSeung-Wook ChiKwang-Hee Bae; Sunhong Kim; S Cho; S Kang; Jeong Hoon KimSung Goo Park
Article
142 2016

2016Article

Graphene oxide induces apoptotic cell death in endothelial cells by activating autophagy via calcium-dependent phosphorylation of c-Jun N-terminal kinasesActa Biomaterialia, vol. 46, pp. 191-203Mi-Hee Lim; I C Jeung; Jin Young JeongSung Jin Yoon; Sang Hyun Lee; Jongjin Park; Yu-Seon Kang; Hansu Lee; Young-Jun ParkHee Gu Lee, et al.
Article
143 2016

2016Article

Crucial role of HMGA1 in the self-renewal and drug resistance of ovarian cancer stem cellsExperimental and Molecular Medicine, vol. 48, pp. e255-e255D K Kim; E J Seo; E J Choi; S I Lee; Y W Kwon; I H Jang; S C Kim; K H Kim; D S Suh; S J Kim, et al.
Article
144 2016

2016Article

Complete mitochondrial genome of the blind vent crab Gandalfus puia (Crustacea: Bythograeidae) from the Tonga ArcMitochondrial DNA Part A, vol. 27, no. 4, pp. 2719-2720Se-Joo Kim; J W Moon; S J Ju
Article
145 2016

2016Article

New records of two pleurostomatids (Ciliophora: Litostomatea) from KoreaJournal of Species Research, vol. 5, no. 3, pp. 343-347Se-Joo Kim; G S Min
Article
146 2016

2016Article

An ethnically relevant consensus Korean reference genome is a step towards personal reference genomesNature Communications, vol. 7, pp. 13637-13637Y S Cho; H Kim; H M Kim; S Jho; J Jun; Y J Lee; K S Chae; C G Kim; S Kim; A Eriksson, et al.
Article
147 2016

2016Article

Heterogeneous niche activity of Ex-Vivo expanded MSCs as factor for variable outcomes in hematopoietic recoveryPLoS One, vol. 11, no. 12, pp. e0168036-e0168036J H Kim; H S Lee; H K Choi; J A Kim; In-Sun Chu; S H Leem; I H Oh
Article
148 2015

2015Article

Identification of the regulators binding to the upstream region of glxR in Corynebacterium glutamicumJournal of Microbiology and Biotechnology, vol. 25, no. 8, pp. 1216-1226B Subhadra; D Ray; J Y Han; Kwang-Hee Bae; J K Lee
Article
149 2015

2015Article

The evolutionary dynamics of highly pathogenic avian influenza H5N1 in south-central Vietnam reveals multiple clades evolving from Chinese and Cambodian virusesComparative Immunology Microbiology and Infectious Diseases, vol. 42, pp. 21-30T H Nguyen; V T Than; H D Thanh; V Q Nguyen; K H Nguyen; D T Nguyen; J H Park; I S Chung; Dae Gwin Jeong; Kyu Tae Chang, et al.
Article
150 2015

2015Article

Taxonomic redescription of Loxophyllum perihoplophorum and L. rostratum (Ciliophora: Pleurostomatida) from KoreaAnimal Systematics, Evolution and Diversity, vol. 31, no. 4, pp. 277-283Se Joo Kim; G S Min
Article
151 2015

2015Article

Activation of EZH2 and SUZ12 regulated by E2F1 predicts the disease progression and aggressive characteristics of bladder cancerClinical Cancer Research, vol. 21, no. 23, pp. 5391-5403S R Lee; Y G Roh; Seon-Kyu Kim; J S Lee; S Y Seol; H H Lee; W T Kim; W J Kim; J Heo; H J Cha, et al.
Article
152 2015

2015Article

Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesisBiochemical and Biophysical Research Communications, vol. 467, no. 2, pp. 211-217Y L Cho; Jeong Ki Min; K M Roh; Won Kon KimBaek Soo HanKwang-Hee Bae; Sang Chul Lee; S J Chung; H J Kang
Article
153 2015

2015Article

Loss of NDRG2 promotes epithelial-mesenchymal transition of gallbladder carcinoma cells through MMP-19-mediated Slug expressionJournal of Hepatology, vol. 63, no. 6, pp. 1429-1439Dong Gwang Lee; Sang Hyun Lee; Jang Seong Kim; Jongjin Park; Y L Cho; K S Kim; D Y Jo; I C Song; N Kim; H J Yun, et al.
Article
154 2015

2015Article

Isolation of foreign material-free endothelial progenitor cells using CD31 aptamer and therapeutic application for ischemic injuryPLoS One, vol. 10, no. 7, pp. e0131785-e0131785J W Yoon; I H Jang; S C Heo; Y W Kwon; E J Choi; Kwang-Hee Bae; D S Suh; S C Kim; S Han; S Haam, et al.
Article
155 2015

2015Article

Histone H3 is digested by granzyme A during compromised cell death in the Raji cellsJournal of Microbiology and Biotechnology, vol. 25, no. 9, pp. 1578-1582Phil Young Lee; Byoung Chul ParkSeung-Wook ChiKwang-Hee Bae; Sunhong Kim; S Cho; Jeong Hoon KimSung Goo Park
Article
156 2015

2015Article

Silica nanoparticles inhibit brown adipocyte differentiation via regulation of p38 phosphorylationNanotechnology, vol. 26, no. 43, pp. 435101-435101Min Jeong Son; Won Kon Kim; M Kwak; Kyoung Jin Oh; W S Chang; Jeong Ki Min; Sang Chul Lee; N W Song; Kwang-Hee Bae
Article
157 2015

2015Article

MKP kinase phosphatase 3 inhibits brown adipocyte differentiation via regulation of Erk phosphorylationMolecular and Cellular Endocrinology, vol. 416, pp. 70-76Won Kon KimKyoung Jin Oh; Hye Ryung Choi; Anna Park; Baek Soo HanSeung-Wook ChiSeung Jun KimKwang-Hee Bae; Sang Chul Lee
Article
158 2015

2015Article

Gecko proteins induce the apoptosis of bladder cancer 5637 cells by inhibiting Akt and activating the intrinsic caspase cascadeBMB Reports, vol. 48, no. 9, pp. 531-536G Y Kim; S Y Park; A Jo; M Kim; S H Leem; W J Jun; S I Shim; Sang Chul Lee; J W Chung
Article
159 2015

2015Article

A database of gene expression profiles of Korean cancer genomeGenomics & Informatics, vol. 13, no. 3, pp. 86-89Seon-Kyu Kim; In-Sun Chu
Article
160 2015

2015Article

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinomaOncotarget, vol. 6, no. 9, pp. 7182-7194Sang Hyun Lee; I C Jeung; T W Park; Kungmin Lee; Dong Gwang Lee; Y L Cho; T S Lee; H J Na; Young-Jun ParkHee Gu Lee, et al.
Article
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