Metabolic Regulation Research Center (대사제어연구센터)681

연구분야

  • 대사성 질환 조절 연구
    • 제2형 당뇨병 및 비만에서의 에너지 대사체계규명 및 제어기전 연구
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    • 저분자 화합물 또는 천연물 기반 대사질환 조절물질 스크리닝 및 기능연구
    • 동물모델을 이용한 대사이상 및 개선 상황에서의 주요 대사기관의 기능변화 및 신호전달 체계 분석
    • 오믹스 분석을 통한 대사기관 간 네트워크 조절인자 발굴 및 기능연구
  • 신경퇴행성 질환 대사조절연구
    • 신경세포의 기능 및 신경퇴행성 질환과 관련 대사체 연구 및 동물 모델 연구
  • 대식세포에 의한 당뇨 및 황반변성의 억제기전 연구
    • 대식세포의 대사조절 기전 연구
    • 대식세포의 감염병 억제 및 신호전달 조절 기전 규명
  • 암대사 제어 기전 연구
    • 화합물을 이용한 암대사 관련 표적분자 도출 및 기능조절 연구
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Showing results 1 to 20 of 633

No. Year Title Type
1 2021

2021Article

Molecular analysis of the interaction between human PTPN21 and the oncoprotein E7 from human papillomavirus genotype 18Molecules and Cells, vol. 44, no. 1, pp. 26-37Hye Seon Lee; Min Wook Kim; K S Jin; Ho-Chul ShinWon Kon KimSang Chul LeeSeung Jun KimEun-Woo LeeBonsu Ku
Article
2 2021

2021Article

Human gut microbiota Agathobaculum butyriciproducens improves cognitive impairment in LPS-induced and APP/PS1 mouse models of Alzheimer's diseaseNutrition Research, vol. 86, pp. 96-108Jun Go; Dong-Ho Chang; Young-Kyoung Ryu; Hey-Yeon Park; In-Bok LeeJung Ran Noh; D Y Hwang; Byoung Chan KimKyoung Shim KimChul-Ho Lee
Article
3 2021

2021Article

Structural and biochemical characterization of EFhd1/Swiprosin-2, an actin-binding protein in mitochondriaFrontiers in Cell and Developmental Biology, vol. 8, pp. 628222-628222S A Mun; J Park; K R Park; Youngjin Lee; J Y Kang; T Park; M Jin; J Yang; C D Jun; S H Eom
Article
4 2021

2021Article

GADD45b regulates hepatic gluconeogenesis via modulating the protein stability of FoxO1Biomedicines, vol. 9, pp. 50-50Hyunmi Kim; Da Som Lee; Tae Hyeon An; Tae Jun Park; Eun-Woo LeeBaek Soo HanWon Kon KimChul-Ho LeeSang Chul LeeKyoung-Jin Oh, et al.
Article
5 2021

2021Article

Myonectin inhibits adipogenesis in 3T3-L1 preadipocytes by regulating p38 MAPK pathwayBMB Reports, vol. 54, no. 2, pp. 124-129Tae Jun Park; Anna Park; J Kim; J Y Kim; Baek Soo HanKyoung-Jin OhEun-Woo LeeSang Chul LeeKwang-Hee BaeWon Kon Kim
Article
6 2021

2021Article

Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activationCell Death and Differentiation, vol. 20, pp. 628-4Sang-Hyun Lee; J M Kim; Dong Gwang LeeJangwook LeeJong Gil ParkTae-Su HanHyun-Soo ChoYoung Lai ChoKwang-Hee BaeYoung-Jun Park, et al.
Article
7 2021

2021Article

Heminiphilus faecis gen. nov., sp. nov., a member of the family Muribaculaceae, isolated from mouse faeces and emended description of the genus MuribaculumAntonie Van Leeuwenhoek International Journal of General and Molecular Microbiology, vol. 114, pp. 275-286Jun Kyu Park; Dong-Ho ChangMoon Soo RheeHaeyoung Jeong; J Song; B J Ku; S B Kim; N Lee; Byoung Chan Kim
Article
8 2021

2021Article

Lipid metabolism and ferroptosisBiology-Basel, vol. 10, no. 3, pp. 184-184Ji-Yoon Lee; Won Kon KimKwang-Hee BaeSang Chul LeeEun-Woo Lee
Article
9 2021

2021Article

Metabolic spectrum of liver failure in type 2 diabetes and obesity: from NAFLD to NASH to HCCInternational Journal of Molecular Sciences, vol. 22, no. 9, pp. 4495-4495Hyunmi Kim; Da Som Lee; Tae Hyeon An; Hyun-Ju Park; Won Kon KimKwang-Hee BaeKyoung-Jin Oh
Article
10 2021

2021Article

Mitochondrial transplantation as a novel therapeutic strategy for mitochondrial diseasesInternational Journal of Molecular Sciences, vol. 22, no. 9, pp. 4793-4793Anna Park; Mihee Oh; Su Jeong Lee; Kyoung-Jin OhEun-Woo LeeSang Chul LeeKwang-Hee BaeBaek Soo HanWon Kon Kim
Article
11 2021

2021Article

Reduced virulence of the MARTX toxin increases the persistence of outbreak-associated Vibrio vulnificus in host reservoirsJournal of Biological Chemistry, vol. 296, pp. 100777-100777Sanghyeon Choi; B S Kim; Jungwon HwangMyung Hee Kim
Article
12 2020

2020Article

Ischemia-induced Netrin-4 promotes neovascularization through endothelial progenitor cell activation via Unc-5 Netrin receptor BFASEB Journal, vol. 34, no. 1, pp. 1231-1246Na Geum Lee; I C Jeung; S C Heo; Jinhoi Song; Wooil Kim; Byungtae Hwang; Min-Gi Kwon; Yeon-Gu KimJangwook LeeJong Gil Park, et al.
Article
13 2020

2020Article

Rapid differentiation of astrocytes from human embryonic stem cellsNeuroscience Letters, vol. 716, pp. 134681-134681Jeong Su Byun; Cheon Ok Lee; Mihee Oh; Dongwook Cha; Won Kon KimKyung Jin OhKwang-Hee BaeSang Chul LeeBaek Soo Han
Article
14 2020

2020Article

Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicityAutophagy, vol. 16, no. 1, pp. 86-105J S Park; D H Lee; Y S Lee; E Oh; Kwang-Hee BaeKyoung-Jin Oh; Hyunmi Kim; S H Bae
Article
15 2020

2020Article

Cathepsin K inhibition-induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x-mediated Bim protein stabilizationRedox Biology, vol. 30, pp. 101422-101422S U Seo; S M Woo; Min Wook Kim; H S Lee; S H Kim; S C Kang; Eun Woo Lee; K J Min; T K Kwon
Article
16 2020

2020Article

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer developmentNature Chemical Biology, vol. 16, no. 1, pp. 31-41S Lim; H Y Cho; D G Kim; Y Roh; S Y Son; A U Mushtaq; M Kim; D Bhattarai; A Sivaraman; Youngjin Lee, et al.
Article
17 2020

2020Article

The transcription factor PITX1 drives astrocyte differentiation by regulating the SOX9 geneJournal of Biological Chemistry, vol. 295, no. 39, pp. 13677-13690Jeong Su ByunMihee Oh; Seonha Lee; Jung-Eun Gil; Yeajin Mo; Bonsu KuWon Kon KimKyoung-Jin OhEun-Woo LeeKwang-Hee Bae, et al.
Article
18 2020

2020Article

IDH1-dependent α-KG regulates brown fat differentiation and function by modulating histone methylationMetabolism-Clinical and Experimental, vol. 105, pp. 154173-154173Hyun Sup Kang; Jae Ho Lee; Kyoung-Jin OhEun-Woo LeeBaek Soo Han; K Y Park; J M Suh; Jeong Ki MinSeung-Wook ChiSang Chul Lee, et al.
Article
19 2020

2020Article

MARTX toxin-stimulated interplay between human cells and Vibrio vulnificusmSphere, vol. 5, no. 4, pp. e00659-20-e00659-20Byoung Sik Kim; Jong-Hwan Kim; Sanghyeon Choi; Shinhye Park; Eun-Young Lee; Serry Koh; Choong-Min RyuSeon-Young KimMyung Hee Kim
Article
20 2020

2020Article

Structure of the MICU1-MICU2 heterodimer provides insights into the gatekeeping threshold shiftIUCRJ, vol. 7, no. 2, pp. 355-365J Park; Youngjin Lee; T Park; J Y Kang; S A Mun; M Jin; J Yang; S H Eom
Article
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