Natural Product Research Center (천연물연구센터)872

연구분야

  • 국내/해외 식물자원의 식물추출물 라이브러리 구축
  • 만성염증질환(천식/COPD, atopy 등) 치료용 천연물소재 개발
  • 대사성질환(비만, 당뇨) 치료용 천연물소재 개발
  • 기능성 유전체학 및 단백체학에 근거한 천식/COPD 생체지표 개발
  • 천연물대사체를 이용한 약용자원의 원산지판별 및 표준화
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Showing results 1 to 20 of 517

No. Year Title Type
1 2022

2022Article

Optimization of chiisanoside and chiisanogenin isolation from Eleutherococcus sessiliflorus (Rupr. & Maxim.) leaves for industrial application: a pilot studyIndustrial Crops and Products, vol. 185, pp. 115099-115099Hyun-Jae Jang; Won Jun Kim; Su Ui LeeMun-Ock Kim; Mi Hyeon Park; Soobin Song; Doo-Young Kim; Seong Mi Lee; H J Yuk; D Y Lee, et al.
Article
2 2022

2022Article

Daphnodorin C isolated from the stems of Daphne kiusiana Miquel attenuates airway inflammation in a mouse model of chronic obstructive pulmonary diseasePhytomedicine, vol. 96, pp. 153848-153848Hyung Won RyuJae-Won LeeMun-Ock Kim; Ro-Woon Lee; Myung Ji Kang; Seong Man Kim; Jaehong Min; Eunsol Oh; Yu Na Song; Sunin Jung, et al.
Article
3 2022

2022Article

Effects of 3'-isovaleryl-4'-senecioylkhellactone from Peucedanum japonicum Thunberg on PMA-stimulated inflammatory response in A549 human lung epithelial cellsJournal of Microbiology and Biotechnology, vol. 32, no. 1, pp. 81-90Dasul Hwang; Hyung Won Ryu; Ji Won Park; Jung Hee KimDoo-Young Kim; Jaehoon Oh; Ok-Kyoung Kwon; S B Han; Kyung Seop Ahn
Article
4 2022

2022Article

Black ginseng extract suppresses airway inflammation induced by cigarette smoke and lipopolysaccharides in vivoAntioxidants, vol. 11, no. 4, pp. 679-679Mun-Ock KimJae-Won Lee; J K Lee; Yu Na Song; Eun Sol Oh; H Ro; D Yoon; Yun Hwa Jeong; Ji-Yoon Park; S T Hong, et al.
Article
5 2022

2022Article

Compound K ameliorates airway inflammation and mucus secretion through the regulation of PKC signaling in vitro and in vivoJournal of Ginseng Research, vol. 46, no. 3, pp. 496-504Jae-Won LeeMun-Ock Kim; Yu Na Song; Jae-Hong Min; Seong Man Kim; Myung Ji Kang; Eun Sol Oh; Ro-Woon Lee; Sunin Jung; H Ro, et al.
Article
6 2022

2022Article

Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cellsEuropean Journal of Pharmacology, vol. 923, pp. 174938-174938Mincheol Kwon; Taehoon Oh; Mina Jang; Gun-Hee Kim; Jung Hee KimHyung Won RyuSei-Ryang OhJae-Hyuk JangJong Seog AhnSung-Kyun Ko
Article
7 2022

2022Article

Methyl p-hydroxycinnamate exerts anti-inflammatory effects in mouse models of lipopolysaccharide-induced ARDS = 급성호흡부전 마우스 모델에서 Methyl p-hydroxycinnamate의 보호 효과Molecular Medicine Reports, vol. 25, no. 1, pp. 37-37Seong Man Kim; Jae-Hong Min; Jung Hee Kim; Jinseon Choi; Jin-Mi Park; Juhyun Lee; Soo Hyeon Goo; Jae Hoon Oh; Seung-Ho Kim; W Chun, et al.
Article
8 2022

2022Article

Protective effect of Paulownia tomentosa fruits in an experimental animal model of acute lung injuryMicrobiology and Biotechnology Letters, vol. 50, no. 2, pp. 310-318Seong Man Kim; Hyung Won RyuOk-Kyoung Kwon; J H Min; Jin Mi Park; Doo-Young KimSei-Ryang Oh; S J Lee; Kyung Seop AhnJae-Won Lee
Article
9 2022

2022Article

Metabolites identification for major active components of Agastache rugosa in rat by UPLC-Orbitap-MS: Comparison of the difference between metabolism as a single component and as a component in a multi-component extractJournal of Pharmaceutical and Biomedical Analysis, vol. 220, pp. 114976-114976A K Jang; M M Rashid; G Lee; Doo-Young KimHyung Won RyuSei-Ryang Oh; J Park; H Lee; J Hong; B H Jung
Article
10 2022

2022Article

Kasugamycin is a novel chitinase 1 inhibitor with strong antifibrotic effects on pulmonary fibrosisAmerican Journal of Respiratory Cell and Molecular Biology, vol. 67, no. 3, pp. 309-319J H Lee; C M Lee; J H Lee; Mun-Ock Kim; J W Park; S Kamle; B Akosman; E L Herzog; X Y Peng; J A Elias, et al.
Article
11 2021

2021Article

The role of macrophages in the development of acute and chronic inflammatory lung diseasesCells, vol. 10, no. 4, pp. 897-897Jae-Won Lee; W Chun; H J Lee; Jae-Hong Min; Seong Man Kim; Ji-Yun Seo; Kyung Seop AhnSei-Ryang Oh
Article
12 2021

2021Article

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesisDevelopmental Cell, vol. 56, no. 8, pp. 1118-1130H Kim; Y S Lee; Seokmin Kim; S Jang; H Choi; Jae-Won LeeTae-Don Kim; V N Kim
Article
13 2021

2021Article

3,4,5-Trihydroxycinnamic acid exerts anti-inflammatory effects on TNF-α/IFN-γ-stimulated HaCaT cellsMolecular Medicine Reports, vol. 24, no. 1, pp. 509-509Ji Won Park; Jae-Hoon Oh; Daseul Hwang; Seong Man Kim; Jae-Hong Min; Ji-Yun Seo; W Chun; H J Lee; Sei-Ryang OhJae-Won Lee, et al.
Article
14 2021

2021Article

Chemical and biological profiles of Dendrobium in two different species, their hybrid, and gamma-irradiated mutant lines of the hybrid based on LC-QToF MS and cytotoxicity analysisPlants-Basel, vol. 10, no. 7, pp. 1376-1376B Nam; Hyun-Jae Jang; A R Han; Y R Kim; C H Jin; C H Jung; K B Kang; S H Kim; M J Hong; J B Kim, et al.
Article
15 2021

2021Article

The role of microglia in the development of neurodegenerative diseases = 신경퇴행성 질환의 발병에서 미세아교세포의 역할Biomedicines, vol. 9, no. 10, pp. 1449-1449Jae-Won Lee; W Chun; H J Lee; Seong-Man Kim; Jae-Hong Min; Doo-Young KimMun-Ock KimHyung Won RyuSu Ui Lee
Article
16 2021

2021Article

Transforming growth factor β inhibits MUC5AC expression by Smad3/HDAC2 complex formation and NF-κB deacetylation at K310 in NCI-H292 cellsMolecules and Cells, vol. 44, no. 1, pp. 38-49Su Ui LeeMun-Ock Kim; Myung Ji Kang; Eun Sol Oh; H Ro; Ro-Woon Lee; Yu Na Song; Sunin Jung; Jae-Won LeeSoo Yun Lee, et al.
Article
17 2021

2021Article

A combination of Olea europaea leaf extract and Spirodela polyrhiza extract alleviates atopic dermatitis by modulating immune balance and skin barrier function in a 1-chloro-2,4-dinitrobenzene-induced murine modelPhytomedicine, vol. 82, pp. 153407-153407Y S Lee; Hyung Won Ryu; W K Yang; Mi Hyeon Park; Y C Park; Doo-Young Kim; H J Kwon; S Y Kim; Sei-Ryang Oh; S H Kim
Article
18 2021

2021Article

8-Epi-xanthatin induces the apoptosis of DU145 prostate carcinoma cells through signal transducer and activator of transcription 3 inhibition and reactive oxygen species generationPhytotherapy Research, vol. 35, pp. 1508-1520Yujin Lee; Jiyeon Choi; Yae Jin Yoon; Yugyeong Sim; Hyung Won RyuSei-Ryang OhDoo-Young Kim; Jihyun Hwang; Seung-Wook ChiDong Cho Han, et al.
Article
19 2021

2021Article

Selecting marker substances of main producing area of Codonopsis lanceolata in Korea using UPLC-QTOF-MS analysis = UPLC-QTOF-MS 분석을 이용한 국내산 더덕 주산지의 표지물질 선정Journal of Applied Biological Chemistry, vol. 64, no. 3, pp. 245-251Young Min An; Hyun-Jae JangDoo-Young Kim; N I Baek; Sei-Ryang Oh; D Y Lee; Hyung Won Ryu
Article
20 2021

2021Article

Anti-inflammatory effects of Lagerstroemia ovalifolia Teijsm. & Binn. in TNFα/IFNγ-stimulated keratinocytes = 라저스트로에미아 오발리폴리아의 항염 효과Evidence-Based Complementary and Alternative Medicine, vol. 2021, pp. 2439231-2439231Han-Sol Lee; Jin Hyub PaikOk-Kyoung Kwon; I Paryanto; P Yuniato; Hyung Won RyuSang-Ho ChoiSei-Ryang Oh; S B Han; Ji Won Park, et al.
Article
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