Natural Product Research Center (천연물연구센터)857

연구분야

  • 국내/해외 식물자원의 식물추출물 라이브러리 구축
  • 만성염증질환(천식/COPD, atopy 등) 치료용 천연물소재 개발
  • 대사성질환(비만, 당뇨) 치료용 천연물소재 개발
  • 기능성 유전체학 및 단백체학에 근거한 천식/COPD 생체지표 개발
  • 천연물대사체를 이용한 약용자원의 원산지판별 및 표준화
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Showing results 1 to 20 of 549

No. Year Title Type
1 2024

2024Article

Anti-inflammatory herbal extracts and their drug discovery perspective in atopic dermatitisBiomolecules & Therapeutics, vol. 32, no. 1, pp. 25-37Jae-Won Lee; E N Kim; G S Jeong
Article
2 2024

2024Article

Inhibition of α-melanocyte-stimulating hormone-induced melanogenesis and molecular mechanisms by polyphenol-enriched fraction of Tagetes erecta L. flowerPhytomedicine, vol. 126, pp. 155442-155442S S Sanjaya; Mi Hyeon Park; W A H M Karunarathne; K T Lee; Y H Choi; C H Kang; M H Lee; M J Jung; Hyung Won Ryu; G Y Kim
Article
3 2024

2024Article

Rotundifuran induces ferroptotic cell death and mitochondria permeability transition in lung cancer cellsBiomedicines, vol. 12, no. 3, pp. 576-576Myung Ji Kang; D O Moon; Ji-Yoon Park; Namho Kim; Su Hyeon Lee; Hyung Won Ryu; Y H Huh; Hyun Sun Lee; Mun-Ock Kim
Article
4 2024

2024Article

Five new meroterpenes from the seeds of Psoralea corylifolia and their diacylglycerol acyltransferase activityPhytochemistry Letters, vol. 61, pp. 16-20X Shao; M X Xiu; X H Wang; W H Xu; Y X Xiao; Y Gao; Y R Jiang; T T Bei; Hyun Sun Lee; L Cui
Article
5 2023

2023Article

Polyacetylenes from the adventitious roots of Centella asiatica with glucose uptake stimulatory activityJournal of Biotechnology, vol. 368, pp. 53-59Y H Jo; S W Yeon; J H Ahn; A Turk; Q Liu; Mun-Ock Kim; B Y Hwang; S Y Park; M K Lee
Article
6 2023

2023Article

A modifiable universal cotinine-chimeric antigen system of NK cells with multiple targetsFrontiers in Immunology, vol. 13, pp. 1089369-1089369Hee Young Kang; Soo Yun Lee; H M Kim; Su Ui Lee; H Lee; M Y Cho; Se-Chan Oh; Seok-Min Kim; H S Park; E H Han, et al.
Article
7 2023

2023Article

Potent xanthine oxidase inhibitory activity of constituents of Agastache rugosa (Fisch. and C.A.Mey.) KuntzeFoods, vol. 12, no. 3, pp. 573-573H J Yuk; Hyung Won Ryu; D S Kim
Article
8 2023

2023Article

Quercetin attenuates the production of pro-inflammatory cytokines in H292 human lung epithelial cells infected with Pseudomonas aeruginosa, by modulating ExoS productionJournal of Microbiology and Biotechnology, vol. 33, no. 4, pp. 430-440H I Ahn; Hyun-Jae JangOk-Kyoung KwonJung Hee Kim; Jae-Hoon Oh; Seung-Ho Kim; Sei-Ryang Oh; S B Han; Kyung Seop Ahn; Ji Won Park
Article
9 2023

2023Article

Diplacone isolated from Paulownia tomentosa mature fruit induces ferroptosis-mediated cell death through mitochondrial Ca2+ influx and mitochondrial permeability transitionInternational Journal of Molecular Sciences, vol. 24, no. 8, pp. 7057-7057Myung Ji Kang; Hyung Won Ryu; Eun Sol Oh; Yu Na Song; Y H Huh; Ji-Yoon Park; Seon Min Oh; Su-Yeon Lee; Yhun Jung Park; Doo-Young Kim, et al.
Article
10 2023

2023Article

Extraction of seven major compounds from Agastache rugosa (Fisch. & C.A.Mey.) Kuntze: optimization study using response surface methodologyJournal of Applied Biological Chemistry, vol. 66, no. 1, pp. 81-89Yang Hee Jo; Seong Mi Lee; Doo-Young Kim; Y Song; H Kim; M K Lee; Sei-Ryang OhHyung Won Ryu
Article
11 2023

2023Article

Three new sesquilignans from the stems of Eleutherococcus senticosus and their bioactivitiesPhytochemistry Letters, vol. 55, pp. 38-43Y Zhang; Y M Zhao; X J Shao; X H Wang; T T Bei; Y R Jiang; W H Xu; Hyun Sun Lee; M X Xiu; J Song, et al.
Article
12 2023

2023Article

Theophylline attenuates BLM-induced pulmonary fibrosis by inhibiting Th17 differentiationInternational Journal of Molecular Sciences, vol. 24, no. 2, pp. 1019-1019Soo-Jin Park; Hwa-Jeong Hahn; Sei-Ryang OhHyun-Jun Lee
Article
13 2023

2023Article

Verproside, the most active ingredient in YPL-001 isolated from Pseudolysimachion rotundum var. subintegrum, decreases inflammatory response by inhibiting PKCδ activation in human lung epithelial cellsInternational Journal of Molecular Sciences, vol. 24, no. 8, pp. 7229-7229Eun Sol Oh; Hyung Won RyuMun-Ock KimJae-Won Lee; Yu Na Song; Ji-Yoon Park; Doo-Young Kim; H Ro; Jinhyuk LeeTae-Don Kim, et al.
Article
14 2023

2023Article

Aged black garlic (Allium sativum L.) and aged black elephant garlic (Allium ampeloprasum L.) alleviate obesity and attenuate obesity-induced muscle atrophy in diet-induced obese C57BL/6 miceBiomedicine & Pharmacotherapy, vol. 163, pp. 114810-114810J Chae; E Lee; Seon Min Oh; Hyung Won Ryu; S Kim; J O Nam
Article
15 2023

2023Article

Bioactive ellagitannins and phenylpropanoid glycosides from the seed of Torreya grandisPhytochemistry Letters, vol. 57, pp. 172-176X H Wang; X J Shao; Y R Jiang; T T Bei; W H Xu; B W Ren; Hyun Sun Lee; L Cui
Article
16 2023

2023Article

Discovery of a novel BLT2 antagonist for the treatment of inflammatory airway diseasesEuropean Journal of Medicinal Chemistry, vol. 261, pp. 115864-115864H Park; D S Harmalkar; J D Wei; S Sun; J Kwon; C H Lee; J G Song; Jin Mi Park; Jae-Won LeeKyung Seop Ahn, et al.
Article
17 2023

2023Article

Black ginseng extract exerts potentially anti-asthmatic activity by inhibiting the protein kinase Cθ-mediated IL-4/STAT6 signaling pathwayInternational Journal of Molecular Sciences, vol. 24, no. 15, pp. 11970-11970Yu Na Song; Jae-Won LeeHyung Won Ryu; J K Lee; Eun Sol Oh; Doo-Young Kim; H Ro; D Yoon; Ji-Yoon Park; S T Hong, et al.
Article
18 2023

2023Article

Dual impact of IGF2 on alveolar stem cell function during tobacco-induced injury repair and development of pulmonary emphysema and cancerCancer Research, vol. 83, no. 11, pp. 1782-1799H J Boo; H Y Min; C S Park; J S Park; J Y Jeong; S Y Lee; W Y Kim; Jae-Won LeeSei-Ryang Oh; R W Park, et al.
Article
19 2023

2023Article

Comparisons of phenolic compounds and antioxidant activities during different growth stages in Artemisia gmelinii Weber ex Stechm with UPLC-QTOF/MS based on a metabolomics approachIndustrial Crops and Products, vol. 202, pp. 116999-116999Seon Min Oh; Doo-Young Kim; Su-Yeon Lee; Ha Eun Song; In Seon Kim; W D Seo; J H Lee; Sei-Ryang Oh; D Y Lee; Hyung Won Ryu
Article
20 2023

2023Article

Assessment of iridoid profiles in the growth period of aerial parts of Pseudolysimachion rotundum var. subintegrum and their antioxidant and MUC5AC inhibitory potentialApplied Biological Chemistry, vol. 66, no. 1, pp. 43-43Soobin Song; Doo-Young Kim; Seon Min Oh; So-Yeun Woo; Il-Joo Kim; Mun-Ock Kim; Ji-Yoon Park; Namho Kim; Hye Young Kim; J Lee, et al.
Article
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