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Natural Product Research Center (천연물연구센터)856

연구분야

국내/해외 식물자원의 식물추출물 라이브러리 구축
만성염증질환(천식/COPD, atopy 등) 치료용 천연물소재 개발
대사성질환(비만, 당뇨) 치료용 천연물소재 개발
기능성 유전체학 및 단백체학에 근거한 천식/COPD 생체지표 개발
천연물대사체를 이용한 약용자원의 원산지판별 및 표준화

Showing results 1 to 20 of 542

No.	Year	Title	Type
1	2023	2023Article Polyacetylenes from the adventitious roots of Centella asiatica with glucose uptake stimulatory activityJournal of Biotechnology, vol. 368, pp. 53-59Y H Jo; S W Yeon; J H Ahn; A Turk; Q Liu; Mun-Ock Kim; B Y Hwang; S Y Park; M K Lee	Article
2	2023	2023Article A modifiable universal cotinine-chimeric antigen system of NK cells with multiple targetsFrontiers in Immunology, vol. 13, pp. 1089369-1089369Hee Young Kang; Soo Yun Lee; H M Kim; Su Ui Lee; H Lee; M Y Cho; Se-Chan Oh; Seok-Min Kim; H S Park; E H Han, et al.	Article
3	2023	2023Article Potent xanthine oxidase inhibitory activity of constituents of Agastache rugosa (Fisch. and C.A.Mey.) KuntzeFoods, vol. 12, no. 3, pp. 573-573H J Yuk; Hyung Won Ryu; D S Kim	Article
4	2023	2023Article Quercetin attenuates the production of pro-inflammatory cytokines in H292 human lung epithelial cells infected with Pseudomonas aeruginosa, by modulating ExoS productionJournal of Microbiology and Biotechnology, vol. 33, no. 4, pp. 430-440H I Ahn; Hyun-Jae Jang; Ok-Kyoung Kwon; Jung Hee Kim; Jae-Hoon Oh; Seung-Ho Kim; Sei-Ryang Oh; S B Han; Kyung Seop Ahn; Ji Won Park	Article
5	2023	2023Article Diplacone isolated from Paulownia tomentosa mature fruit induces ferroptosis-mediated cell death through mitochondrial Ca2+ influx and mitochondrial permeability transitionInternational Journal of Molecular Sciences, vol. 24, no. 8, pp. 7057-7057Myung Ji Kang; Hyung Won Ryu; Eun Sol Oh; Yu Na Song; Y H Huh; Ji-Yoon Park; Seon Min Oh; Su-Yeon Lee; Yhun Jung Park; Doo-Young Kim, et al.	Article
6	2023	2023Article Extraction of seven major compounds from Agastache rugosa (Fisch. & C.A.Mey.) Kuntze: optimization study using response surface methodologyJournal of Applied Biological Chemistry, vol. 66, no. 1, pp. 81-89Yang Hee Jo; Seong Mi Lee; Doo-Young Kim; Y Song; H Kim; M K Lee; Sei-Ryang Oh; Hyung Won Ryu	Article
7	2023	2023Article Three new sesquilignans from the stems of Eleutherococcus senticosus and their bioactivitiesPhytochemistry Letters, vol. 55, pp. 38-43Y Zhang; Y M Zhao; X J Shao; X H Wang; T T Bei; Y R Jiang; W H Xu; Hyun Sun Lee; M X Xiu; J Song, et al.	Article
8	2023	2023Article Theophylline attenuates BLM-induced pulmonary fibrosis by inhibiting Th17 differentiationInternational Journal of Molecular Sciences, vol. 24, no. 2, pp. 1019-1019Soo-Jin Park; Hwa-Jeong Hahn; Sei-Ryang Oh; Hyun-Jun Lee	Article
9	2023	2023Article Verproside, the most active ingredient in YPL-001 isolated from Pseudolysimachion rotundum var. subintegrum, decreases inflammatory response by inhibiting PKCδ activation in human lung epithelial cellsInternational Journal of Molecular Sciences, vol. 24, no. 8, pp. 7229-7229Eun Sol Oh; Hyung Won Ryu; Mun-Ock Kim; Jae-Won Lee; Yu Na Song; Ji-Yoon Park; Doo-Young Kim; H Ro; Jinhyuk Lee; Tae-Don Kim, et al.	Article
10	2023	2023Article Aged black garlic (Allium sativum L.) and aged black elephant garlic (Allium ampeloprasum L.) alleviate obesity and attenuate obesity-induced muscle atrophy in diet-induced obese C57BL/6 miceBiomedicine & Pharmacotherapy, vol. 163, pp. 114810-114810J Chae; E Lee; Seon Min Oh; Hyung Won Ryu; S Kim; J O Nam	Article
11	2023	2023Article Bioactive ellagitannins and phenylpropanoid glycosides from the seed of Torreya grandisPhytochemistry Letters, vol. 57, pp. 172-176X H Wang; X J Shao; Y R Jiang; T T Bei; W H Xu; B W Ren; Hyun Sun Lee; L Cui	Article
12	2023	2023Article Discovery of a novel BLT2 antagonist for the treatment of inflammatory airway diseasesEuropean Journal of Medicinal Chemistry, vol. 261, pp. 115864-115864H Park; D S Harmalkar; J D Wei; S Sun; J Kwon; C H Lee; J G Song; Jin Mi Park; Jae-Won Lee; Kyung Seop Ahn, et al.	Article
13	2023	2023Article 1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surfaceOcular Surface, vol. 29, pp. 469-479C H Yoon; Hyun-Jae Jang; J S Ryu; J H Ko; Kyung Seop Ahn; Sei-Ryang Oh; J H Oh; J H Chung; J Y Oh	Article
14	2023	2023Article Black ginseng extract exerts potentially anti-asthmatic activity by inhibiting the protein kinase Cθ-mediated IL-4/STAT6 signaling pathwayInternational Journal of Molecular Sciences, vol. 24, no. 15, pp. 11970-11970Yu Na Song; Jae-Won Lee; Hyung Won Ryu; J K Lee; Eun Sol Oh; Doo-Young Kim; H Ro; D Yoon; Ji-Yoon Park; S T Hong, et al.	Article
15	2023	2023Article Dual impact of IGF2 on alveolar stem cell function during tobacco-induced injury repair and development of pulmonary emphysema and cancerCancer Research, vol. 83, no. 11, pp. 1782-1799H J Boo; H Y Min; C S Park; J S Park; J Y Jeong; S Y Lee; W Y Kim; Jae-Won Lee; Sei-Ryang Oh; R W Park, et al.	Article
16	2023	2023Article Comparisons of phenolic compounds and antioxidant activities during different growth stages in Artemisia gmelinii Weber ex Stechm with UPLC-QTOF/MS based on a metabolomics approachIndustrial Crops and Products, vol. 202, pp. 116999-116999Seon Min Oh; Doo-Young Kim; Su-Yeon Lee; Ha Eun Song; In Seon Kim; W D Seo; J H Lee; Sei-Ryang Oh; D Y Lee; Hyung Won Ryu	Article
17	2023	2023Article Assessment of iridoid profiles in the growth period of aerial parts of Pseudolysimachion rotundum var. subintegrum and their antioxidant and MUC5AC inhibitory potentialApplied Biological Chemistry, vol. 66, no. 1, pp. 43-43Soobin Song; Doo-Young Kim; Seon Min Oh; So-Yeun Woo; Il-Joo Kim; Mun-Ock Kim; Ji-Yoon Park; Namho Kim; Hye Young Kim; J Lee, et al.	Article
18	2023	2023Article Methyl lucidone inhibits airway inflammatory response by reducing TAK1 activity in human bronchial epithelial NCI？H292 cellsHeliyon, vol. 9, no. 9, pp. e20154-e20154Eun Sol Oh; H Ro; Hyung Won Ryu; Yu Na Song; Ji-Yoon Park; Namho Kim; Hae Young Kim; Seon Min Oh; Su-Yeon Lee; Doo-Young Kim, et al.	Article
19	2023	2023Article Potent inhibition of human tyrosinase inhibitor by verproside from the whole plant of Pseudolysimachion rotundum var. subintegrumJournal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, pp. 2252198-2252198Sunin Jung; So Yeun Woo; Mi Hyeon Park; Doo-Young Kim; Su Ui Lee; Sei-Ryang Oh; Mun-Ock Kim; Jinhyuk Lee; Hyung Won Ryu	Article
20	2023	2023Article The tobacco-specific carcinogen NNK induces pulmonary tumorigenesis via nAChR/Src/STAT3-mediated activation of the renin-angiotensin system and IGF-1R signalingExperimental and Molecular Medicine, vol. 55, no. 6, pp. 1131-1144H J Boo; H Y Min; S J Hwang; H J Lee; Jae-Won Lee; Sei-Ryang Oh; C S Park; J S Park; Y M Lee; H Y Lee	Article

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