고분비성 단백질의 스크리닝 및 재조합 단백질의 생성을 위한 융합 파트너로서 그의 용도

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Title
고분비성 단백질의 스크리닝 및 재조합 단백질의 생성을 위한 융합 파트너로서 그의 용도
Alternative Title
Screening of abundantly secreted proteins and their use as fusion partners for the production of recombinant proteins
Inventor(s)
손정훈; 김현진; 임광묵; 배정훈
Assignee(s)
한국생명공학연구원(소)
Application No.
12/631,449 (2009.12.04)
Registration No.
9,550,997 (2017.01.24)
Country
미국
Abstract
The present invention relates techniques for identifying suitable secretion fusion partner (SFP) for hyper-secretory production of recombinant proteins. The SFPs can be obtained from secretome analyzes. Recombinant proteins are produced in a fusion form with a secretion fusion partner (SFP) and can be separated from the SFP by in vitro protease treatment. SFPs of this invention greatly improve the secretion level of target proteins and peptides which are valuable for bio-pharmaceuticals and the bio-industry.
Type
Patent
Appears in Collections:
Synthetic Biology and Bioengineering Research Institute > Synthetic Biology Research Center > 2. Patents
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