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- 신규한 GPCR 단백질 및 이의 용도
- Alternative Title
- A NOVEL G PROTEIN COUPLED RECEPTOR AND A USE THEREOF
- 유향숙; 이희구; 송은영; 최정해; 원미선; 안지원; 정경숙; 염영일
- Application No.
- 13/322,304 (2011.11.23)
- Registration No.
- 9,034,327 (2015.05.19)
- Disclosed are novel GPCR (G Protein Coupled Receptor) proteins and genes encoding the same. Also provided is the use of the proteins and the genes. Particularly, contemplated are a novel GPCR (G Protein Coupled Receptor) polypeptide, a polynucleotide coding for the same, a recombinant vector carrying the polynucleotide or a fragment thereof, host cells transformed with the vector, a transgenic animal infected with the vector. Also, a composition for detecting a cancer marker, comprising an agent capable of measuring the expression level of mRNA or protein of the GPCR polynucleotide, a kit for the diagnosis of cancer, comprising the composition, and a method for detecting the GPCR polypeptide and a gene encoding the polypeptide are provided. Further, a composition for the treatment and prevention of cancer, comprising an oligonucleotide inhibiting the expression of a gene encoding the GPCR polypeptide or an antibody against the GPCR protein, and a method for screening a modulator of the GPCR protein or a cancer therapeutic agent are provided.
- Appears in Collections:
- Division of Biomedical Research > Immunotherapy Research Center > 2. Patents
Division of Biomedical Research > Personalized Genomic Medicine Research Center > 2. Patents
Division of Research on National Challenges > Stem Cell Convergenece Research Center > 2. Patents
Division of Research on National Challenges > 2. Patents
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