메타게놈 유래 알칼린 포스파타아제

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Title
메타게놈 유래 알칼린 포스파타아제
Alternative Title
Alkaline Phosphatase derived from Metagenome
Inventor(s)
이승구; 최수림; 송재준나유진
Assignee(s)
한국생명공학연구원
Application No.
13/519,013 (2012.06.25)
Registration No.
8647854 (2014.02.11)
Country
미국
Abstract
The present invention relates to a metagenome-derived alkaline phosphatase, and more particularly to a novel, metagenome-derived alkaline phosphatase screened using a artificial genetic circuit that detects phenolic compounds, and a preparation method thereof. A novel alkaline phosphatase according to the present invention has high activity of dephosphorylating DNA and can be inactivated rapidly by simple heat treatment. Thus, it can be used for a dephosphorylation reaction so that genetic manipulations, including genetic cloning, become efficient. In addition, it can be actively expressed in recombinant microorganisms, and thus can be used in various assays, including enzyme immunoassay.
Type
Patent
Appears in Collections:
Synthetic Biology and Bioengineering Research Institute > 2. Patents
Division of Bio Technology Innovation > SME Support Center > 2. Patents
Synthetic Biology and Bioengineering Research Institute > Synthetic Biology Research Center > 2. Patents
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