활성성분을 다량 함유한 산꼬리풀 정제 분획물, 이의 제조방법 및 이를 유효성분으로 포함하는 염증, 알레르기 및 천식의 예방 또는 치료용 조성물

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Title
활성성분을 다량 함유한 산꼬리풀 정제 분획물, 이의 제조방법 및 이를 유효성분으로 포함하는 염증, 알레르기 및 천식의 예방 또는 치료용 조성물
Alternative Title
A PURIFIED EXTRACT ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM CONTAINING ABUNDANT AMOUNT OF ACTIVE INGREDIENT, THE PREPARATION THEREOF, AND THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATION,
Inventor(s)
오세량안경섭; 이형규; 송혁환; 김정희권옥경김두영
Assignee(s)
영진약품공업주식회사,한국생명공학연구원
Application No.
2,951,501 (2016.12.14)
Registration No.
2,951,501 (2019.10.15)
Country
캐나다
Abstract
The present invention relates to inventive novel industrialized method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of Pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti- inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinolphil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and golblet cell hyperplasia in a OVA-sensitized/challenged mouse model.
Type
Patent
Appears in Collections:
Ochang Branch Institute > 2. Patents
Ochang Branch Institute > Natural Product Research Center > 2. Patents
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