Production of flavonoids in callus cultures of Sophora flavescens Aiton

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dc.contributor.authorJi-Sun Park-
dc.contributor.authorZuh Kyung Seong-
dc.contributor.authorMi Sun Kim-
dc.contributor.authorJang Ho Ha-
dc.contributor.authorKi-Beom Moon-
dc.contributor.authorHyo Jun Lee-
dc.contributor.authorHyeong Kyu Lee-
dc.contributor.authorJae Heung Jeon-
dc.contributor.authorS U Park-
dc.contributor.authorHyun Soon Kim-
dc.date.accessioned2020-09-24T03:23:09Z-
dc.date.available2020-09-24T03:23:09Z-
dc.date.issued2020-
dc.identifier.issn2223-7747-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/22678-
dc.description.abstractFlavonoids, including maackiain (Maac) from Sophora flavescens Aiton roots, have many pharmacological properties, such as antitumor, antimicrobial, and antifungal activities. This research aimed to develop an in vitro plant and callus culture system for S. flavescens for the purpose of generating an alternative production system for enhancing Maac production, as Maac is usually present in very small amounts in S. flavescens’ roots. We arranged the optimal conditions of different tissues of S. flavescens and supplemented the medium with various plant growth regulators (PGRs). The highest induction and proliferation rates of callus was shown in combination treatments of all concentrations of thidiazuron (TDZ) and picloram. In addition, calli induced with leaf explants cultured on 2.0 mg/L picloram and 0.5 mg/L 6-benzyladenine (BA) in Murashige and Skoog (MS) medium had the highest accumulation of the active metabolite Maac. In vitro shoots were regenerated on medium containing combinations of TDZ and α-Naphthalene acetic acid (NAA). A reliable protocol for the mass production of secondary metabolites using a callus culture of S. flavescens was successfully established.-
dc.publisherMDPI-
dc.titleProduction of flavonoids in callus cultures of Sophora flavescens Aiton-
dc.title.alternativeProduction of flavonoids in callus cultures of Sophora flavescens Aiton-
dc.typeArticle-
dc.citation.titlePlants-Basel-
dc.citation.number0-
dc.citation.endPage688-
dc.citation.startPage688-
dc.citation.volume9-
dc.contributor.affiliatedAuthorJi-Sun Park-
dc.contributor.affiliatedAuthorZuh Kyung Seong-
dc.contributor.affiliatedAuthorMi Sun Kim-
dc.contributor.affiliatedAuthorJang Ho Ha-
dc.contributor.affiliatedAuthorKi-Beom Moon-
dc.contributor.affiliatedAuthorHyo Jun Lee-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.affiliatedAuthorJae Heung Jeon-
dc.contributor.affiliatedAuthorHyun Soon Kim-
dc.contributor.alternativeName박지선-
dc.contributor.alternativeName성주경-
dc.contributor.alternativeName김미선-
dc.contributor.alternativeName하장호-
dc.contributor.alternativeName문기범-
dc.contributor.alternativeName이효준-
dc.contributor.alternativeName이형규-
dc.contributor.alternativeName전재흥-
dc.contributor.alternativeName박상운-
dc.contributor.alternativeName김현순-
dc.identifier.bibliographicCitationPlants-Basel, vol. 9, pp. 688-688-
dc.identifier.doi10.3390/plants9060688-
dc.subject.keywordCallus induction-
dc.subject.keywordHerbal resource-
dc.subject.keywordPlant growth regulators-
dc.subject.keywordSecondary metabolite-
dc.subject.keywordSophora flavescens-
dc.subject.localCallus induction-
dc.subject.localHerbal resource-
dc.subject.localplant growth regulators-
dc.subject.localPlant growth regulators-
dc.subject.localSecondary metabolites-
dc.subject.localsecondary metabolites-
dc.subject.localSecondary metabolite-
dc.subject.localsecondary metabolite-
dc.subject.localSophora flavescens-
dc.subject.localsophora flavescens-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Plant Systems Engineering Research > 1. Journal Articles
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