Open Access@KRIBBSynthetic Biology and Bioengineering Research InstituteSynthetic Biology Research Center2. Patents
TAG-72에 대한 인간화 항체
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- Title
- TAG-72에 대한 인간화 항체
- Alternative Title
- Humanized Anti-TAG-72 Monoclonal Antibodies
- Inventor(s)
- 홍효정; 윤선옥; 김상직; 장명희
- Assignee(s)
- 한국생명공학연구원(소)
- Application No.
- 2,569,200 (2006.11.29)
- Registration No.
- 2569200 (2014.07.15)
- Country
- 캐나다
- Abstract
- The present invention relates to humanized antibodies specific to a tumor-associated glycoprotein, TAG-72, and anticancer compositions comprising the humanized antibodies. In detail, the present invention relates to a humanized antibody which has enhanced antigen binding affinity by mutating a heavy chain of a humanized antibody PXA/HzK specific for TAG-72, an antibody which is prepared by replacing a light chain of the humanized antibody with a human light chain, and anticancer compositions including the antibodies.
- Type
- Patent
- Appears in Collections:
- Synthetic Biology and Bioengineering Research Institute > Synthetic Biology Research Center > 2. Patents
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