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- 항-ＦＡＳＮ 자가면역 항체를 포함하는 간암 진단 마커 및 이의 항원을 포함하는 간암 진단용 조성물
- Alternative Title
- A marker comprising anti-FASN autoantibodies and a composition comprising antigen thereof for diagnosing liver cancer
- 유향숙; 고정헌; 황해민; 허창규; 우미경; 조은위
- Application No.
- 13/501,426 (2012.04.11)
- Registration No.
- 8,658,769 (2014.02.25)
- The present invention relates to an autoantibody specifically recognizing the epitope sequence of FASN (fatty acid synthase), more particularly, to the autoantibody or a fragment comprising an antigen-binding site thereof, a diagnostic composition for hepatocellular carcinoma comprising an agent capable of assessing the expression level of the autoantibody, a hybridoma cell line producing the autoantibody, a diagnostic kit for hepatocellular carcinoma comprising the composition, a method for detecting the autoantibody of hepatocellular carcinoma patient using the composition, and a method for screening a therapeutic agent for hepatocellular carcinoma by administering candidate materials for hepatocellular carcinoma treatment to confirm a reduction in the expression level of autoantibody.
- Appears in Collections:
- Synthetic Biology and Bioengineering Research Institute > Genome Editing Research Center > 2. Patents
Division of Biomedical Research > Rare Disease Research Center > 2. Patents
- Files in This Item:
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