Cytoplasmic MYC is an anti-necroptotic protein

Cited 3 time in scopus
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dc.contributor.authorEun-Woo Lee-
dc.contributor.authorD Seong-
dc.contributor.authorJ Song-
dc.date.accessioned2020-11-17T09:23:01Z-
dc.date.available2020-11-17T09:23:01Z-
dc.date.issued2020-
dc.identifier.issn2372-3556-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/23495-
dc.description.abstractCancer cells are often resistant to necroptosis as well as apotosis, but the underlying mechanisms are not fully understood. We recently revealed an important crosstalk between MYC, a potent oncogene, and receptor-interacting protein kinase 3 (RIPK3), a pivotal factor in inducing necroptosis. Mechanistically, cytoplasmic MYC directly binds to RIPK3, inhibiting initial necrosome complex formation.-
dc.publisherT&F (Taylor & Francis)-
dc.titleCytoplasmic MYC is an anti-necroptotic protein-
dc.title.alternativeCytoplasmic MYC is an anti-necroptotic protein-
dc.typeArticle-
dc.citation.titleMolecular & Cellular Oncology-
dc.citation.number6-
dc.citation.endPagee1817697-
dc.citation.startPagee1817697-
dc.citation.volume7-
dc.contributor.affiliatedAuthorEun-Woo Lee-
dc.contributor.alternativeName이은우-
dc.contributor.alternativeName성대현-
dc.contributor.alternativeName송재환-
dc.identifier.bibliographicCitationMolecular & Cellular Oncology, vol. 7, no. 6, pp. e1817697-e1817697-
dc.identifier.doi10.1080/23723556.2020.1817697-
dc.subject.keywordMYC-
dc.subject.keywordRIPK1-
dc.subject.keywordRIPK3-
dc.subject.keywordnecroptosis-
dc.subject.keywordTNF-
dc.subject.localMYC-
dc.subject.localRIPK1-
dc.subject.localRIPK3-
dc.subject.localNecroptosis-
dc.subject.localnecroptosis-
dc.subject.localTNF-
dc.description.journalClassN-
Appears in Collections:
Division of A.I. & Biomedical Research > Metabolic Regulation Research Center > 1. Journal Articles
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