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- Title
- Current status of COVID-19 vaccine development: focusing on antigen design and clinical trials on later stages
- Author(s)
- Pureum Lee; Chang-Ung Kim; S H Seo; Doo-Jin Kim
- Bibliographic Citation
- Immune Network, vol. 21, no. 1, pp. e4-e4
- Publication Year
- 2021
- Abstract
- The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.
- Keyword
- COVID-19VaccinesPrefusion-stabilizedVAERDAntibody-dependent enhancementPre-existing immunological memory
- ISSN
- 1598-2629
- Publisher
- Korea Soc-Assoc-Inst
- DOI
- http://dx.doi.org/10.4110/in.2021.21.e4
- Type
- Article
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
- Files in This Item:
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