DC Field | Value | Language |
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dc.contributor.author | Gil Soo Kim | - |
dc.contributor.author | Jun-Pil Jang | - |
dc.contributor.author | Taehoon Oh | - |
dc.contributor.author | Min Cheol Kwon | - |
dc.contributor.author | Byeong San Lee | - |
dc.contributor.author | Jung-Sook Lee | - |
dc.contributor.author | Sung-Kyun Ko | - |
dc.contributor.author | Young-Soo Hong | - |
dc.contributor.author | Jong Seog Ahn | - |
dc.contributor.author | Jae-Hyuk Jang | - |
dc.date.accessioned | 2021-07-10T03:30:29Z | - |
dc.date.available | 2021-07-10T03:30:29Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/24474 | - |
dc.description.abstract | Two angucyclines, pseudonocardones D (1) and E (2), were isolated from Streptomyces sp. KCB15JA151. The planar structure was elucidated by comprehensive spectroscopic analysis. The absolute configuration of the sugar unit was determined based on the basis of coupling constants, ROESY, chemical derivatization and HPLC analysis. The biological activities of compounds 1 and 2 were examined by performing a computational target prediction, which led to tests of the antiestrogenic activity. The result suggested that compound 1 might be an ERα antagonist. | - |
dc.publisher | Elsevier | - |
dc.title | Angucyclines containing β-D-glucuronic acid from Streptomyces sp. KCB15JA151 | - |
dc.title.alternative | Angucyclines containing β-D-glucuronic acid from Streptomyces sp. KCB15JA151 | - |
dc.type | Article | - |
dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
dc.citation.number | 0 | - |
dc.citation.endPage | 128237 | - |
dc.citation.startPage | 128237 | - |
dc.citation.volume | 48 | - |
dc.contributor.affiliatedAuthor | Gil Soo Kim | - |
dc.contributor.affiliatedAuthor | Jun-Pil Jang | - |
dc.contributor.affiliatedAuthor | Taehoon Oh | - |
dc.contributor.affiliatedAuthor | Min Cheol Kwon | - |
dc.contributor.affiliatedAuthor | Byeong San Lee | - |
dc.contributor.affiliatedAuthor | Jung-Sook Lee | - |
dc.contributor.affiliatedAuthor | Sung-Kyun Ko | - |
dc.contributor.affiliatedAuthor | Young-Soo Hong | - |
dc.contributor.affiliatedAuthor | Jong Seog Ahn | - |
dc.contributor.affiliatedAuthor | Jae-Hyuk Jang | - |
dc.contributor.alternativeName | 김길수 | - |
dc.contributor.alternativeName | 장준필 | - |
dc.contributor.alternativeName | 오태훈 | - |
dc.contributor.alternativeName | 권민철 | - |
dc.contributor.alternativeName | 이병산 | - |
dc.contributor.alternativeName | 이정숙 | - |
dc.contributor.alternativeName | 고성균 | - |
dc.contributor.alternativeName | 홍영수 | - |
dc.contributor.alternativeName | 안종석 | - |
dc.contributor.alternativeName | 장재혁 | - |
dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 48, pp. 128237-128237 | - |
dc.identifier.doi | 10.1016/j.bmcl.2021.128237 | - |
dc.subject.keyword | Streptomyces sp. | - |
dc.subject.keyword | Angucycline | - |
dc.subject.keyword | β-D-Glucuronic acid | - |
dc.subject.local | Streptomyces sp | - |
dc.subject.local | Streptomyces sp. | - |
dc.subject.local | streptomyces sp. | - |
dc.subject.local | Angucycline | - |
dc.subject.local | β-D-Glucuronic acid | - |
dc.description.journalClass | Y | - |
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