Colorimetric paper sensor for visual detection of date-rape drug γ-hydroxybutyric acid (GHB) = GHB 검출 키트

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Title
Colorimetric paper sensor for visual detection of date-rape drug γ-hydroxybutyric acid (GHB) = GHB 검출 키트
Author(s)
Seong Uk Son; Soojin Jang; Byunghoon Kang; J Kim; Jaewoo Lim; Seungbeom Seo; Taejoon KangJuyeon JungKyu-Sun Lee; H Kim; Eun Kyung Lim
Bibliographic Citation
Sensors and Actuators B-Chemical, vol. 347, pp. 130598-130598
Publication Year
2021
Abstract
Drug-facilitated crimes using date-rape drugs are on the rise. Gamma-hydroxybutyric acid (GHB), a notorious date-rape drug, is colorless, odorless, and tasteless, and therefore difficult to detect in beverages. The ingestion of GHB can severely incapacitate individuals by inducing dizziness, drowsiness, and unconsciousness, making them vulnerable to crimes. To prevent drug-facilitated crimes, a GHB detection kit is developed in which PCDA-gabazine and PCDA, which strongly interact with GHB, are used as sensing materials, while PEO and PVDF are used as matrix materials that enable rapid GHB detection in a short time by increasing the penetration rate of the liquid samples. Detection kits are fabricated by electrospinning a solution containing the sensing materials and matrix materials mixed in an optimal ratio. The color of the kit distinctly changes from blue to red when a drink spiked with GHB is dropped on it (limit of detection: about 0.0096 wt%). The fabricated GHB detection kit is easy to carry and provides a visually distinguishable detection result without requiring any complicated procedure, equipment, or trained personnel. Importantly, the kit can detect GHB in colored and alcoholic beverages. Furthermore, a mobile application is developed that can aid GHB detection using the kit in diverse environments.
Keyword
Colorimetric detectionDate-rape drugGHB detectionPaper sensorPolydiacetylene nanosheet
ISSN
0925-4005
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/j.snb.2021.130598
Type
Article
Appears in Collections:
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
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