Graphene field-effect transistor based high-performance wireless portable device for H1N1 detection

Abstract

In this study, a convenient high-performance portable sensor platform for simple, fast, and efficient detection of H1N1 virus is demonstrated using a graphene-based transistor type architecture. A uniform graphene layer was generated and patterned by conventional methods such as lithography and vapor deposition, subsequently, electrodes were introduced on the patterned graphene layer to obtain transistor type sensor geometry. Then, the graphene surface was functionalized with antibody for H1N1 virus detection and sensor performance test. The transition curve, linearity, and sensitivity (10 pfu/mL) of the sensor component were measured. In addition, the portable H1N1 diagnosis platform for simple, fast, and convenient virus detection was produced and demonstrated. Consequently, the sensor performance was maintained in the portable sensor platform compared with the graphene-based sensor component. This presented portable H1N1 diagnosis platform showed better performance than the lateral flow assay.