Selecting marker substances of main producing area of Codonopsis lanceolata in Korea using UPLC-QTOF-MS analysis = UPLC-QTOF-MS 분석을 이용한 국내산 더덕 주산지의 표지물질 선정

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dc.contributor.authorYoung Min An-
dc.contributor.authorHyun-Jae Jang-
dc.contributor.authorDoo-Young Kim-
dc.contributor.authorN I Baek-
dc.contributor.authorSei-Ryang Oh-
dc.contributor.authorD Y Lee-
dc.contributor.authorHyung Won Ryu-
dc.date.accessioned2021-10-19T15:30:50Z-
dc.date.available2021-10-19T15:30:50Z-
dc.date.issued2021-
dc.identifier.issn1229-2737-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/24924-
dc.description.abstractCodonopsis lanceolata (Deoduk) was grown in East Asia, including Korea, China, Japan, and Russia, and the roots of C. lanceolata have been used as functional foods and traditional medicine to treat symptoms of cough, bronchitis, asthma, tuberculosis, and dyspepsia. The phytochemicals of C. lanceolata have been reported such as phenylpropanoids, polyacetylenes, saponins, and flavonoids that are involved in pharmacological effects such as anti-obesity, anti-inflammation, anti-tumor, anti-oxidant, and anti-microbial activities. Selecting marker substances of the main producing area by MS-based metabolomics analysis is important to ensure the beneficial effect of C. lanceolata without side-effects because differences in cultivated areas of plants were related not only to the safety of medicinal plants but also to changes in chemical composition and biological efficacy. In our present study, ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry combined with multivariate statistical analysis was applied to recognize the main producing area of C. lanceolata in South Korea. As a result of Principal Component Analysis and loading plot analysis of three groups, Inje (Kangwon-do), Hoengseong (Kangwon-do), and Muju (Jeonlabuk-do), several secondary metabolites of C. lanceolata including tangshenoside I, lancemaside A, and lancemaside G, were suggested as potential marker substances to distinguish the place of main producing area of C. lanceolata.-
dc.publisherSpringer-
dc.titleSelecting marker substances of main producing area of Codonopsis lanceolata in Korea using UPLC-QTOF-MS analysis = UPLC-QTOF-MS 분석을 이용한 국내산 더덕 주산지의 표지물질 선정-
dc.title.alternativeSelecting marker substances of main producing area of Codonopsis lanceolata in Korea using UPLC-QTOF-MS analysis-
dc.typeArticle-
dc.citation.titleJournal of Applied Biological Chemistry-
dc.citation.number3-
dc.citation.endPage251-
dc.citation.startPage245-
dc.citation.volume64-
dc.contributor.affiliatedAuthorYoung Min An-
dc.contributor.affiliatedAuthorHyun-Jae Jang-
dc.contributor.affiliatedAuthorDoo-Young Kim-
dc.contributor.affiliatedAuthorSei-Ryang Oh-
dc.contributor.affiliatedAuthorHyung Won Ryu-
dc.contributor.alternativeName안영민-
dc.contributor.alternativeName장현재-
dc.contributor.alternativeName김두영-
dc.contributor.alternativeName백남인-
dc.contributor.alternativeName오세량-
dc.contributor.alternativeName이대영-
dc.contributor.alternativeName류형원-
dc.identifier.bibliographicCitationJournal of Applied Biological Chemistry, vol. 64, no. 3, pp. 245-251-
dc.identifier.doi10.3839/jabc.2021.034-
dc.subject.keywordCodonopsis lanceolata-
dc.subject.keywordLancemaside-
dc.subject.keywordMetabolomics-
dc.subject.keywordPrincipal Component Analysis-
dc.subject.keywordTangshenoside I-
dc.subject.keywordUltraperformance liquid chromatography quadrupole time-of-flight mass spectrometry-
dc.subject.localCodonopsis lanceolata-
dc.subject.localcodonopsis lanceolata-
dc.subject.localLancemaside-
dc.subject.localMetabolomics-
dc.subject.localmetabolomics-
dc.subject.localprincipal component analysis (PCA)-
dc.subject.localPrincipal Component Analysis-
dc.subject.localPrincipal component analysis (PCA)-
dc.subject.localprincipal component analysis-
dc.subject.localprincipal components analysis-
dc.subject.localPrincipal component analysis-
dc.subject.localTangshenoside I-
dc.subject.localUltraperformance liquid chromatography quadrupole time-of-flight mass spectrometry-
dc.subject.localUltra-performance liquid chromatography to quadrupole time-offlight mass spectrometry-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
Ochang Branch Institute > 1. Journal Articles
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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