DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hyunjung Cha | - |
dc.contributor.author | Hyeran Kim | - |
dc.contributor.author | Y Joung | - |
dc.contributor.author | Hyunju Kang | - |
dc.contributor.author | Jeong Moon | - |
dc.contributor.author | Hyowon Jang | - |
dc.contributor.author | S Park | - |
dc.contributor.author | Hyung-Jun Kwon | - |
dc.contributor.author | In Chul Lee | - |
dc.contributor.author | S Kim | - |
dc.contributor.author | D Yong | - |
dc.contributor.author | Sun Woo Yoon | - |
dc.contributor.author | S G Park | - |
dc.contributor.author | Kyeonghye Guk | - |
dc.contributor.author | Eun Kyung Lim | - |
dc.contributor.author | H G Park | - |
dc.contributor.author | J Choo | - |
dc.contributor.author | Juyeon Jung | - |
dc.contributor.author | Taejoon Kang | - |
dc.date.accessioned | 2022-01-27T15:30:30Z | - |
dc.date.available | 2022-01-27T15:30:30Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 0956-5663 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/25352 | - |
dc.description.abstract | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected humans worldwide for over a year now. Although various tests have been developed for the detection of SARS-CoV-2, advanced sensing methods are required for the diagnosis, screening, and surveillance of coronavirus disease 2019 (COVID-19). Here, we report a surface-enhanced Raman scattering (SERS)-based immunoassay involving an antibody pair, SERS-active hollow Au nanoparticles (NPs), and magnetic beads for the detection of SARS-CoV-2. The selected antibody pair against the SARS-CoV-2 antigen, along with the magnetic beads, facilitates the accurate direct detection of the virus. The hollow Au NPs exhibit strong, reproducible SERS signals, allowing sensitive quantitative detection of SARS-CoV-2. This assay had detection limits of 2.56 fg/mL for the SARS-CoV-2 antigen and 3.4 plaque-forming units/mL for the SARS-CoV-2 lysates. Furthermore, it facilitated the identification of SARS-CoV-2 in human nasopharyngeal aspirates and diagnosis of COVID-19 within 30 min using a portable Raman device. Thus, this assay can be potentially used for the diagnosis and prevention of COVID-19. | - |
dc.publisher | Elsevier | - |
dc.title | Surface-enhanced Raman scattering-based immunoassay for severe acute respiratory syndrome coronavirus 2 | - |
dc.title.alternative | Surface-enhanced Raman scattering-based immunoassay for severe acute respiratory syndrome coronavirus 2 | - |
dc.type | Article | - |
dc.citation.title | Biosensors & Bioelectronics | - |
dc.citation.number | 0 | - |
dc.citation.endPage | 114008 | - |
dc.citation.startPage | 114008 | - |
dc.citation.volume | 202 | - |
dc.contributor.affiliatedAuthor | Hyunjung Cha | - |
dc.contributor.affiliatedAuthor | Hyeran Kim | - |
dc.contributor.affiliatedAuthor | Hyunju Kang | - |
dc.contributor.affiliatedAuthor | Jeong Moon | - |
dc.contributor.affiliatedAuthor | Hyowon Jang | - |
dc.contributor.affiliatedAuthor | Hyung-Jun Kwon | - |
dc.contributor.affiliatedAuthor | In Chul Lee | - |
dc.contributor.affiliatedAuthor | Sun Woo Yoon | - |
dc.contributor.affiliatedAuthor | Kyeonghye Guk | - |
dc.contributor.affiliatedAuthor | Eun Kyung Lim | - |
dc.contributor.affiliatedAuthor | Juyeon Jung | - |
dc.contributor.affiliatedAuthor | Taejoon Kang | - |
dc.contributor.alternativeName | 차현정 | - |
dc.contributor.alternativeName | 김혜란 | - |
dc.contributor.alternativeName | 정연주 | - |
dc.contributor.alternativeName | 강현주 | - |
dc.contributor.alternativeName | 문정 | - |
dc.contributor.alternativeName | 장효원 | - |
dc.contributor.alternativeName | 박소현 | - |
dc.contributor.alternativeName | 권형준 | - |
dc.contributor.alternativeName | 이인철 | - |
dc.contributor.alternativeName | 김선주 | - |
dc.contributor.alternativeName | 용동은 | - |
dc.contributor.alternativeName | 윤선우 | - |
dc.contributor.alternativeName | 박성규 | - |
dc.contributor.alternativeName | 국경혜 | - |
dc.contributor.alternativeName | 임은경 | - |
dc.contributor.alternativeName | 박현규 | - |
dc.contributor.alternativeName | 주재범 | - |
dc.contributor.alternativeName | 정주연 | - |
dc.contributor.alternativeName | 강태준 | - |
dc.identifier.bibliographicCitation | Biosensors & Bioelectronics, vol. 202, pp. 114008-114008 | - |
dc.identifier.doi | 10.1016/j.bios.2022.114008 | - |
dc.subject.keyword | Antibody | - |
dc.subject.keyword | Coronavirus disease 2019 | - |
dc.subject.keyword | Immunoassay | - |
dc.subject.keyword | Nanoparticle | - |
dc.subject.keyword | Surface-enhanced Raman scattering | - |
dc.subject.keyword | Severe acute respiratory syndrome coronavirus 2 | - |
dc.subject.local | Antibodies | - |
dc.subject.local | Antibody | - |
dc.subject.local | antibody | - |
dc.subject.local | Coronavirus disease 2019 | - |
dc.subject.local | Immunoassay | - |
dc.subject.local | Immunoassays | - |
dc.subject.local | immunoassay | - |
dc.subject.local | Nanoparticle | - |
dc.subject.local | Nanoparticles | - |
dc.subject.local | nanoparticle | - |
dc.subject.local | Surface-enhanced Raman scattering | - |
dc.subject.local | surface-enhanced Raman scattering | - |
dc.subject.local | surface-enhanced raman scattering | - |
dc.subject.local | Surface-enhanced Raman Scattering | - |
dc.subject.local | Surface-enhanced Raman scattering (SERS) | - |
dc.subject.local | severe acute respiratory syndrome coronavirus 2 | - |
dc.subject.local | Severe acute respiratory syndrome coronavirus 2 | - |
dc.description.journalClass | Y | - |
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