Electrospun nanofibrous membrane-based colorimetric device for rapid and simple screening of amphetamine-type stimulants in drinks = 암테파민 계열 각성제 스크리닝 키트

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Title
Electrospun nanofibrous membrane-based colorimetric device for rapid and simple screening of amphetamine-type stimulants in drinks = 암테파민 계열 각성제 스크리닝 키트
Author(s)
Soojin Jang; Seong Uk Son; Byunghoon Kang; J Kim; Jaewoo Lim; Seungbeom Seo; Taejoon KangJuyeon JungKyu-Sun Lee; H Kim; Eun Kyung Lim
Bibliographic Citation
Analytical Chemistry, vol. 94, pp. 3535-3542
Publication Year
2022
Abstract
With the growth of drug-facilitated crimes, prevention has become increasingly important. Although various drug detection technologies exist, most focus on postconsumption detection. However, the prevention of drug-facilitated crimes requires technology for the quick and easy detection of amphetamine-type stimulants (ATSs) before ingestion. Herein, drug screening kits (DSKs) were developed for the simple detection of ATSs in drinks. The DSKs consisted of polydiacetylene nanofiber-based paper sensors fabricated by electrospinning with 10,12-pentacosadiynoic acid (PCDA) and PCDA-dopamine as sensing materials that can bind ATSs via hydrogen bonding and π-π interactions. Dropping a drink on the DSK provided an immediate visual indication of the presence of ATSs. When ATSs were present in the drink, the color of the DSK clearly changed from blue to red, with the increase in red intensity being more than twofold greater than that observed when water alone was tested. Notably, the result could be confirmed by the naked eye without any analytical instrumentation. A color change indicating the presence of ATSs was successfully observed in various alcoholic and nonalcoholic drinks. These results indicate the potential of DSKs for preventing drug-facilitated crimes caused by unwanted drug intake.
ISSN
0003-2700
Publisher
Amer Chem Soc
DOI
http://dx.doi.org/10.1021/acs.analchem.1c04512
Type
Article
Appears in Collections:
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
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