Microbiological survey of Korean mouse facilities from 2014 to 2019

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Title
Microbiological survey of Korean mouse facilities from 2014 to 2019
Author(s)
Sang Woon KimHi-Jo ShinSe Hee ParkTeak Chang LeeHae Jin Lee; Og Sung Moon; Ki Hoan NamWon Kee YoonHyoung-Chin Kim; H J Kwon; Young Suk Won
Bibliographic Citation
Experimental Animals, vol. 71, no. 1, pp. 109-115
Publication Year
2022
Abstract
We surveyed mouse microbiological contamination rates by testing rates for common contaminants using serological, culture, and parasitological methods. A total of 21,292 experimentally housed mice from 206 animal facilities, including hospitals, universities, companies, and research institutes, were tested over a 6-year period from 2014 to 2019. The most commonly found contaminants were various species of nonpathogenic protozoa (47.2%). The most common pathogenic bacteria were Staphylococcus aureus (21.2%), Pasteurella pneumotropica (12.5%), and Pseudomonas aeruginosa (5.8%). Mouse hepatitis virus (6.1%) was detected, but no other viral or bacterial pathogens were found. These results establish that the main pathogens that currently contaminate mouse facilities in Korea are opportunistic pathogens and that contamination with important pathogens, such as those in Categories B or C, has decreased.
Keyword
Microbiological monitoringMiceMouse hepatitis virus
ISSN
1341-1357
Publisher
Int Press Editing Centre Inc
DOI
http://dx.doi.org/10.1538/expanim.21-0083
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of Bioinfrastructure > Laboratory Animal Resource Center > 1. Journal Articles
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