Juvenile hormone inhibitory and mosquito larvicidal substances derived from actinomycetes

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Title
Juvenile hormone inhibitory and mosquito larvicidal substances derived from actinomycetes
Author(s)
D H Park; J Y Choi; Jong Hoon Kim; M G Park; M Wang; S H Kim; H Y Lee; Y H Je
Bibliographic Citation
Entomological Research, vol. 52, no. 6, pp. 265-270
Publication Year
2022
Abstract
Mosquitoes are major pests that attack humans and spread pathogens. To control mosquito larvae, insect growth regulators such as methoprene and pyriproxyfen have been widely used. Juvenile hormone antagonists (JHAN) have the potential to act as an eco-friendly insecticide with a novel mode of action. Actinomycetes are known as a producer of an enormous number of secondary metabolites. In this study, secondary metabolites of 232 Actinomycetes strains were screened for their juvenile hormone antagonist activity and their mosquito larvicidal activity. Among them, IMBL-1939, 1952, 2005 and 2064 strains showed mosquito larvicidal activity with JHAN activity. These actinomycetes derived JHAN could be alternative sustainable vector control agents.
Keyword
ActinomycetesAedes albopictusJuvenile hormone antagonistSecondary metabolites
ISSN
1738-2297
Publisher
Wiley
DOI
http://dx.doi.org/10.1111/1748-5967.12587
Type
Article
Appears in Collections:
Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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