Jejuketomycins A and B, polyketide glycosides with cancer cell migration inhibitory activity from Streptomyces sp. KCB15JA151

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dc.contributor.authorJun-Pil Jang-
dc.contributor.authorG S Kim-
dc.contributor.authorTae Hoon Oh-
dc.contributor.authorBeomcheol Park-
dc.contributor.authorMinhee Kim-
dc.contributor.authorGwi Ja Hwnag-
dc.contributor.authorHyeok Won Lee-
dc.contributor.authorJin Gyeom Lee-
dc.contributor.authorYoung-Soo Hong-
dc.contributor.authorJong Seog Ahn-
dc.contributor.authorSung-Kyun Ko-
dc.contributor.authorJae-Hyuk Jang-
dc.date.accessioned2022-08-11T16:32:23Z-
dc.date.available2022-08-11T16:32:23Z-
dc.date.issued2022-
dc.identifier.issn2046-2069-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/30168-
dc.description.abstractTwo new polyketide glycosides jejuketomycins A (1) and B (2), were isolated from a culture of Streptomyces sp. KCB15JA151. Their chemical structures including the absolute configurations were determined by detailed analyses of the NMR and HRMS data and ECD calculations and spectral data. Compounds 1 and 2 possess an unusual 6/6/8 tricyclic ring system. Biological evaluation with the wound healing assay and time-lapse cell tracking analysis revealed that compounds 1 and 2 have significant inhibitory activities against cancer cell migration with low cytotoxicity.-
dc.publisherRoyal Soc Chem-
dc.titleJejuketomycins A and B, polyketide glycosides with cancer cell migration inhibitory activity from Streptomyces sp. KCB15JA151-
dc.title.alternativeJejuketomycins A and B, polyketide glycosides with cancer cell migration inhibitory activity from Streptomyces sp. KCB15JA151-
dc.typeArticle-
dc.citation.titleRSC Advances-
dc.citation.number0-
dc.citation.endPage22366-
dc.citation.startPage22360-
dc.citation.volume12-
dc.contributor.affiliatedAuthorJun-Pil Jang-
dc.contributor.affiliatedAuthorTae Hoon Oh-
dc.contributor.affiliatedAuthorBeomcheol Park-
dc.contributor.affiliatedAuthorMinhee Kim-
dc.contributor.affiliatedAuthorGwi Ja Hwnag-
dc.contributor.affiliatedAuthorHyeok Won Lee-
dc.contributor.affiliatedAuthorJin Gyeom Lee-
dc.contributor.affiliatedAuthorYoung-Soo Hong-
dc.contributor.affiliatedAuthorJong Seog Ahn-
dc.contributor.affiliatedAuthorSung-Kyun Ko-
dc.contributor.affiliatedAuthorJae-Hyuk Jang-
dc.contributor.alternativeName장준필-
dc.contributor.alternativeName김길수-
dc.contributor.alternativeName오태훈-
dc.contributor.alternativeName박범철-
dc.contributor.alternativeName김민희-
dc.contributor.alternativeName황귀자-
dc.contributor.alternativeName이혁원-
dc.contributor.alternativeName이진겸-
dc.contributor.alternativeName홍영수-
dc.contributor.alternativeName안종석-
dc.contributor.alternativeName고성균-
dc.contributor.alternativeName장재혁-
dc.identifier.bibliographicCitationRSC Advances, vol. 12, pp. 22360-22366-
dc.identifier.doi10.1039/d2ra04039e-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
Division of Bio Technology Innovation > BioProcess Engineering Center > 1. Journal Articles
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