Production of ser125-interleukin-2 by site directed mutagenesis
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Seongman Kang | - |
| dc.contributor.author | Ju Won Kwak | - |
| dc.contributor.author | Jong Bum Kwon | - |
| dc.contributor.author | Sung Wan Kim | - |
| dc.contributor.author | In Young Lee | - |
| dc.contributor.author | Sun Bok Lee | - |
| dc.contributor.author | Hye-Young Yun | - |
| dc.contributor.author | Kyung Soo Hahm | - |
| dc.contributor.author | Moon Hi Han | - |
| dc.contributor.author | Doe Sun Na | - |
| dc.date.accessioned | 2017-04-19T08:43:49Z | - |
| dc.date.available | 2017-04-19T08:43:49Z | - |
| dc.date.issued | 1989 | - |
| dc.identifier.issn | 0368-4881 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/3029 | - |
| dc.description.abstract | Human Interleukin-2 (IL-2) posessing a serine in place of cystein at the amino acid sequence position 125 has been produced in E. coll by site directed mutagenesis. The activity of purified Ser125-IL-2 was more than 2.5 times higher than that of Cys125-IL-2 as determined by the growth promoting effect on IL-2 dependent cell line. The yield of production of Ser125-IL-2 was at least 1.5 times higher as compared to that of Cys125-IL-2. | - |
| dc.publisher | Korea Soc-Assoc-Inst | - |
| dc.title | Production of ser125-interleukin-2 by site directed mutagenesis | - |
| dc.title.alternative | Production of ser125-interleukin-2 by site directed mutagenesis | - |
| dc.type | Article | - |
| dc.citation.title | Korean Biochemical Journal | - |
| dc.citation.number | 3 | - |
| dc.citation.endPage | 311 | - |
| dc.citation.startPage | 306 | - |
| dc.citation.volume | 22 | - |
| dc.contributor.affiliatedAuthor | Ju Won Kwak | - |
| dc.contributor.affiliatedAuthor | In Young Lee | - |
| dc.contributor.affiliatedAuthor | Kyung Soo Hahm | - |
| dc.contributor.affiliatedAuthor | Moon Hi Han | - |
| dc.contributor.alternativeName | 강성만 | - |
| dc.contributor.alternativeName | 곽주원 | - |
| dc.contributor.alternativeName | 권종범 | - |
| dc.contributor.alternativeName | 김성완 | - |
| dc.contributor.alternativeName | 이인영 | - |
| dc.contributor.alternativeName | 이선복 | - |
| dc.contributor.alternativeName | 윤혜영 | - |
| dc.contributor.alternativeName | 함경수 | - |
| dc.contributor.alternativeName | 한문희 | - |
| dc.contributor.alternativeName | 나도선 | - |
| dc.identifier.bibliographicCitation | Korean Biochemical Journal, vol. 22, no. 3, pp. 306-311 | - |
| dc.description.journalClass | N | - |
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