Fructan biosynthesis by yeast cell factories

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Title
Fructan biosynthesis by yeast cell factories
Author(s)
Hyunjun Ko; Bong Hyun SungMi-Jin KimJung Hoon SohnJung Hoon Bae
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 32, no. 11, pp. 1373-1381
Publication Year
2022
Abstract
Fructan is a polysaccharide composed of fructose and can be classified into several types, such as inulin, levan, and fructo-oligosaccharides, based on their linkage patterns and degree of polymerization. Owing to its structural and functional diversity, fructan has been used in various fields including prebiotics, foods and beverages, cosmetics, and pharmaceutical applications. With increasing interest in fructans, efficient and straightforward production methods have been explored. Since the 1990s, yeast cells have been employed as producers of recombinant enzymes for enzymatic conversion of fructans including fructosyltransferases derived from various microbes and plants. More recently, yeast cell factories are highlighted as efficient workhorses for fructan production by direct fermentation. In this review, recent advances and strategies for fructan biosynthesis by yeast cell factories are discussed.
Keyword
FructanLevanInulinFructosyltransferaseYeastFermentation
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
DOI
http://dx.doi.org/10.4014/jmb.2207.07062
Type
Article
Appears in Collections:
Synthetic Biology and Bioengineering Research Institute > Synthetic Biology Research Center > 1. Journal Articles
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