Antigenic structure and polyalbumin receptor characteristics of pre-S2 region of hepatitus B virus surface antigen = B형 간염바이러스 표면황원 중 pre-S2 부위의 항원구조 및 중합 인혈청 알부민 수용체의

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Title
Antigenic structure and polyalbumin receptor characteristics of pre-S2 region of hepatitus B virus surface antigen = B형 간염바이러스 표면황원 중 pre-S2 부위의 항원구조 및 중합 인혈청 알부민 수용체의
Author(s)
Hye Young Yun; Pilyon Park; Seung Moak Kim; Kyung Soo Hahm
Bibliographic Citation
Korean Biochemical Journal, vol. 23, no. 2, pp. 232-239
Publication Year
1990
Abstract
Pre-S2 region (amino acids 120-174) of hepatitis B virus surface antigen contains immunodominant and disulfide bond-independent epitopes. Using pre-S2 peptides (recombinant peptides 121-174/adw2, 134-170/adw2 and synthetic peptide 120-145/ayw), epitope and polyalbumin receptor region on pre-S2 were studied. Polyalbumin receptor assay and enzyme immunoassay provided evidences that the region of at least 12 residues (134-145) of pre-S2 was shared by epitope for an anti-pre-S2 monoclonal antibody and polyalbumin receptor. This region was shown to be hydrophilic and a possible 分-sheet.
ISSN
0368-4881
Publisher
Korea Soc-Assoc-Inst
Type
Article
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1. Journal Articles > Journal Articles
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