Hollow fiber bioreactors with internal aeration circuits

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dc.contributor.authorBong Hyun Chung-
dc.contributor.authorHo Nam Chang-
dc.coverage.temporal20160601-20170531-
dc.date.accessioned2017-04-19T08:43:56Z-
dc.date.available2017-04-19T08:43:56Z-
dc.date.issued1990-
dc.identifier.issn0385-6380-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3088-
dc.description.abstractNew hollow fiber bioreactors for aerobic culture were introduced and Aspergillus niger for citric acid production was cultivated as a model system. These reactors consisted of a bundle mixed of hydrophilic membranes for liquid nutrient transport and hydrophobic membranes for gaseous nutrient transport. The cells were successfully cultivated. However, the polymeric hollow fiber membranes were compressed and blocked by excessive fungal cell growth. Citric acid was produced with a high volumetric productivity compared with that of shake-flask fermentation, but the long-term operation was not successful due to a rapid decrease of the production rate.-
dc.publisherSoc Bioscience Bioengineering Japan-
dc.titleHollow fiber bioreactors with internal aeration circuits-
dc.title.alternativeHollow fiber bioreactors with internal aeration circuits-
dc.typeArticle-
dc.citation.titleJournal of Fermentation Bioengineering-
dc.citation.number3-
dc.citation.endPage177-
dc.citation.startPage175-
dc.citation.volume69-
dc.contributor.affiliatedAuthorBong Hyun Chung-
dc.contributor.alternativeName정봉현-
dc.contributor.alternativeName장호남-
dc.identifier.bibliographicCitationJournal of Fermentation Bioengineering, vol. 69, no. 3, pp. 175-177-
dc.identifier.doi10.1016/0922-338X(90)90042-U-
dc.description.journalClassY-
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