Enhanced production of shikonin by Lithospermum erythrorhizon cells immobilized in polyurethane foam matrices

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dc.contributor.authorYoung Hoon Park-
dc.contributor.authorWeon Taek Seo-
dc.contributor.authorJang Ryol Liu-
dc.date.accessioned2017-04-19T08:43:56Z-
dc.date.available2017-04-19T08:43:56Z-
dc.date.issued1990-
dc.identifier.issn0385-6380-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3091-
dc.description.abstractProduction of shikonin by Lithospermum erythrorhizon cells immobilized in polyurethane foam matrices was investigated. The cells were effectively entrapped inside the polymer matrices prepared in a cubic form with a lateral length of 0.5 cm. They proliferated further by incubation and resulted in immobilized and resulted in immobilized polymer foam cubes which were fully packed with cell aggregates. Shikonin production was observed to increase significantly when the immobilized cells were used. It was excreted by the cells and directly adsorbed, by hydrophobic interaction, to the polymer site. The product could be recovered, after the cells were separated, by direct solvent extraction from the shikonin-adsorbed polyurethane matrices. It is more interesting to note that a single-stage culture with immobilized L. erythrorhizon cells yielded higher shikonin productivity than the conventional two-stage culture system, which is considered to be of practical importance for industrial applications.-
dc.publisherSoc Bioscience Bioengineering Japan-
dc.titleEnhanced production of shikonin by Lithospermum erythrorhizon cells immobilized in polyurethane foam matrices-
dc.title.alternativeEnhanced production of shikonin by Lithospermum erythrorhizon cells immobilized in polyurethane foam matrices-
dc.typeArticle-
dc.citation.titleJournal of Fermentation Bioengineering-
dc.citation.number5-
dc.citation.endPage321-
dc.citation.startPage317-
dc.citation.volume70-
dc.contributor.affiliatedAuthorYoung Hoon Park-
dc.contributor.affiliatedAuthorWeon Taek Seo-
dc.contributor.affiliatedAuthorJang Ryol Liu-
dc.contributor.alternativeName박영훈-
dc.contributor.alternativeName서원택-
dc.contributor.alternativeName유장렬-
dc.identifier.bibliographicCitationJournal of Fermentation Bioengineering, vol. 70, no. 5, pp. 317-321-
dc.identifier.doi10.1016/0922-338X(90)90141-I-
dc.subject.keywordshikonin-
dc.subject.keywordimmobilized cell-
dc.subject.keywordplant cell-
dc.subject.keywordlithospermum erythrorhizon-
dc.subject.localshikonin-
dc.subject.localShikonin-
dc.subject.localimmobilized cell-
dc.subject.localPlant Cell-
dc.subject.localplant cell-
dc.subject.locallithospermum erythrorhizon-
dc.subject.localLithospermum erythrorhizon-
dc.description.journalClassY-
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