A site-specific deletion mutant of murine gamma-Interferon showing anti-viral activity in Vitro

Cited 0 time in scopus
Metadata Downloads
Title
A site-specific deletion mutant of murine gamma-Interferon showing anti-viral activity in Vitro
Author(s)
Young Ik Lee
Bibliographic Citation
Molecules and Cells, vol. 1, no. 3, pp. 363-368
Publication Year
1991
Abstract
Four amino acids were deleted in murine y-interferon gene using simple oligonucleotide directed mutagenesis in order to check whether the 4 amino acids were required for the anti-viral activity. Plasmid pYL-2 was constnicted using expression vector pEV-vr£3 and the plasmid pMifko-1 which contains the whole coding sequence for the cDNA and 5'-and 3'-noncoding sequences. Results demonstrated that deletion of the four amino acids from the amino-terminal region of the murine y-interferon still showed anti-viral activity in vitro.
ISSN
1016-8478
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.