Conductive thread-based immunosensor for pandemic influenza A (H1N1) virus detection

Cited 4 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorSeong Uk Son-
dc.contributor.authorSoojin Jang-
dc.contributor.authorJaewoo Lim-
dc.contributor.authorSeung Beom Seo-
dc.contributor.authorTaejoon Kang-
dc.contributor.authorJuyeon Jung-
dc.contributor.authorSeo Yeong Oh-
dc.contributor.authorS W Yoon-
dc.contributor.authorD Yong-
dc.contributor.authorJ Lee-
dc.contributor.authorEun Kyung Lim-
dc.date.accessioned2023-02-17T16:32:47Z-
dc.date.available2023-02-17T16:32:47Z-
dc.date.issued2023-
dc.identifier.issn1944-8244-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/31085-
dc.description.abstractInfectious agents such as viruses pose significant threats to human health, being transmitted via direct contact as well as airborne transmission without direct contact, thus requiring rapid detection to prevent the spread of infectious diseases. In this study, we developed a conductive thread-based immunosensor (CT-IS), a biosensor to easily detect the presence of airborne viruses. CT-IS utilizes an antibody that specifically recognizes the HA protein of the pandemic influenza A (pH1N1) virus, which is incorporated into the conductive thread. The antigen-antibody interaction results in increased strain on the conductive thread in the presence of the pH1N1 virus, resulting in increased electrical resistance of the CT-IS. We evaluated the performance of this sensor using the HA protein and the pH1N1 virus, in addition to samples from patients infected with the pH1N1 virus. We observed a significant change in resistance in the pH1N1-infected patient samples (positive: n = 11, negative: n = 9), whereas negligible change was observed in the control samples (patients not infected with the pH1N1 virus; negative). Hence, the CT-IS is a lightweight fiber-type sensor that can be used as a wearable biosensor by combining it with textiles, to detect the pH1N1 virus in a person's vicinity.-
dc.publisherAmer Chem Soc-
dc.titleConductive thread-based immunosensor for pandemic influenza A (H1N1) virus detection-
dc.title.alternativeConductive thread-based immunosensor for pandemic influenza A (H1N1) virus detection-
dc.typeArticle-
dc.citation.titleACS Applied Materials & Interfaces-
dc.citation.number6-
dc.citation.endPage7766-
dc.citation.startPage7759-
dc.citation.volume15-
dc.contributor.affiliatedAuthorSeong Uk Son-
dc.contributor.affiliatedAuthorSoojin Jang-
dc.contributor.affiliatedAuthorJaewoo Lim-
dc.contributor.affiliatedAuthorSeung Beom Seo-
dc.contributor.affiliatedAuthorTaejoon Kang-
dc.contributor.affiliatedAuthorJuyeon Jung-
dc.contributor.affiliatedAuthorSeo Yeong Oh-
dc.contributor.affiliatedAuthorEun Kyung Lim-
dc.contributor.alternativeName손성욱-
dc.contributor.alternativeName장수진-
dc.contributor.alternativeName임재우-
dc.contributor.alternativeName서승범-
dc.contributor.alternativeName강태준-
dc.contributor.alternativeName정주연-
dc.contributor.alternativeName오서영-
dc.contributor.alternativeName윤선우-
dc.contributor.alternativeName용동은-
dc.contributor.alternativeName이재종-
dc.contributor.alternativeName임은경-
dc.identifier.bibliographicCitationACS Applied Materials & Interfaces, vol. 15, no. 6, pp. 7759-7766-
dc.identifier.doi10.1021/acsami.2c19403-
dc.subject.keywordRespiratory infection-
dc.subject.keywordpH1N1 virus-
dc.subject.keywordConductive thread-
dc.subject.keywordElectric immunosensor-
dc.subject.keywordPoint-of-care detection-
dc.subject.localpH1N1 virus-
dc.subject.localPoint-of-care detection-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.