Open Access@KRIBBOchang Branch InstituteDivision of National Bio-InfrastructureInternational Biological Material Research Center1. Journal Articles
In vitro anti-inflammatory and skin moisturizing properties of Pilea martini (Levl.) Hand.-Mazz. extracts
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | J Choi | - |
| dc.contributor.author | Y Y Jung | - |
| dc.contributor.author | I J Ha | - |
| dc.contributor.author | S H Baek | - |
| dc.contributor.author | Z Zhang | - |
| dc.contributor.author | Soo Yong Kim | - |
| dc.contributor.author | Y Hong | - |
| dc.contributor.author | S Kim | - |
| dc.contributor.author | H W Yeum | - |
| dc.contributor.author | S R Jeon | - |
| dc.contributor.author | K Park | - |
| dc.contributor.author | D Nam | - |
| dc.date.accessioned | 2023-03-07T16:33:34Z | - |
| dc.date.available | 2023-03-07T16:33:34Z | - |
| dc.date.issued | 2020 | - |
| dc.identifier.issn | 1934-578X | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/31350 | - |
| dc.description.abstract | The in vitro anti-inflammatory and skin moisturizing activities of Pilea martini (Levl.) Hand.-Mazz. were investigated on lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and human immortalized keratinocytes. Chromatographic analysis was performed to identify the chemical composition of the extracts. Pilea martini extracts significantly suppressed LPS-induced nitric oxide, prostaglandin E2, interleukin 6, and tumor necrosis factor α production in dose-dependent manners. In addition, the extracts inhibited LPS-induced inducible nitric oxide synthase and cyclooxygenase-2 proteins and their mRNA expression through causing a downregulation of nuclear factor-κB, activator protein 1, and mitogen-activated protein kinase signaling cascades. The extracts increased the production of hyaluronic acid levels and enhanced the expression levels of both filaggrin and serine palmitoyltransferase regulation. Liquid chromatography-mass spectroscopy analysis showed that the extracts contained 6 different compounds (malic acid, tryptophan, chlorogenic acid, caffeic acid, p-coumaric acid, and isoquercetin) that may contribute to their bioactivities. Taken together, Pilea martini extract showed remarkable promise as an anti-inflammatory and moisturizing agent. | - |
| dc.publisher | Sage | - |
| dc.title | In vitro anti-inflammatory and skin moisturizing properties of Pilea martini (Levl.) Hand.-Mazz. extracts | - |
| dc.title.alternative | In vitro anti-inflammatory and skin moisturizing properties of Pilea martini (Levl.) Hand.-Mazz. extracts | - |
| dc.type | Article | - |
| dc.citation.title | Natural Product Communications | - |
| dc.citation.number | 11 | - |
| dc.citation.endPage | 967866 | - |
| dc.citation.startPage | 967866 | - |
| dc.citation.volume | 15 | - |
| dc.contributor.affiliatedAuthor | Soo Yong Kim | - |
| dc.contributor.alternativeName | 최지은 | - |
| dc.contributor.alternativeName | 정영윤 | - |
| dc.contributor.alternativeName | 하인진 | - |
| dc.contributor.alternativeName | 백승호 | - |
| dc.contributor.alternativeName | Zhang | - |
| dc.contributor.alternativeName | 김수용 | - |
| dc.contributor.alternativeName | 홍예진 | - |
| dc.contributor.alternativeName | 김성윤 | - |
| dc.contributor.alternativeName | 염혜원 | - |
| dc.contributor.alternativeName | 전새롬 | - |
| dc.contributor.alternativeName | 박경복 | - |
| dc.contributor.alternativeName | 남동우 | - |
| dc.identifier.bibliographicCitation | Natural Product Communications, vol. 15, no. 11, pp. 967866-967866 | - |
| dc.identifier.doi | 10.1177/1934578X20967866 | - |
| dc.subject.keyword | Pilea martini | - |
| dc.subject.keyword | NF-κB | - |
| dc.subject.keyword | AP-1 | - |
| dc.subject.keyword | MAPKs | - |
| dc.subject.keyword | Filaggrin | - |
| dc.subject.keyword | SPT | - |
| dc.subject.local | NFkappaB | - |
| dc.subject.local | NFκB | - |
| dc.subject.local | Nf-κB | - |
| dc.subject.local | Nf-κb | - |
| dc.subject.local | Nuclear factor (NF)-κB | - |
| dc.subject.local | Nuclear factor kappa B | - |
| dc.subject.local | Nuclear factor kappaB | - |
| dc.subject.local | Nuclear factor κB | - |
| dc.subject.local | Nuclear factor κB (NF-κB) | - |
| dc.subject.local | Nuclear factor-kappa B | - |
| dc.subject.local | Nuclear factor-kappa B (NF-κB) | - |
| dc.subject.local | Nuclear factor-kappaB | - |
| dc.subject.local | Nuclear factor-κB | - |
| dc.subject.local | Nuclear factor-κb | - |
| dc.subject.local | NF-kB | - |
| dc.subject.local | NF-kappa B | - |
| dc.subject.local | NF-kappaB | - |
| dc.subject.local | NF-ΚB | - |
| dc.subject.local | NF-κ B | - |
| dc.subject.local | NF-κB | - |
| dc.subject.local | NF-κB (nuclear factor kappa-B) | - |
| dc.subject.local | nuclear factor kappa B | - |
| dc.subject.local | nuclear factor κB | - |
| dc.subject.local | nuclear factor-kappaB | - |
| dc.subject.local | nuclear factor-kappaB (NF-κB) | - |
| dc.subject.local | nuclear factor-κB | - |
| dc.subject.local | nuclear factorκB | - |
| dc.subject.local | AP-1 | - |
| dc.subject.local | MAPK | - |
| dc.subject.local | MAPKs | - |
| dc.subject.local | Filaggrin | - |
| dc.subject.local | filaggrin | - |
| dc.description.journalClass | Y | - |
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