Utilizing bacteria-derived components for cancer immunotherapy

Abstract

Bacteria-related cancer immunotherapy, because of its mechanisms and useful applications in the induction of anti-tumor immunity, has gained substantial attention in recent decades. Bacteria can enable targeting of tumors, and specifically can colonize the core tumor area. Because they contain many pathogen-associated molecular patterns？which efficiently stimulate immune cells, even within microenvironments that suppress anti-tumor immunity？bacteria boost immunological recognition leading to the destruction of malignant cells. This Editorial highlights various bacteria with immunotherapeutic effects and their by-products used as immunotherapeutics.