Three new sesquilignans from the stems of Eleutherococcus senticosus and their bioactivities
Cited 1 time in 
Metadata Downloads
- Title
- Three new sesquilignans from the stems of Eleutherococcus senticosus and their bioactivities
- Author(s)
- Y Zhang; Y M Zhao; X J Shao; X H Wang; T T Bei; Y R Jiang; W H Xu; Hyun Sun Lee; M X Xiu; J Song; L Cui
- Bibliographic Citation
- Phytochemistry Letters, vol. 55, pp. 38-43
- Publication Year
- 2023
- Abstract
- Three new sesquilignans, Eleutherocosus A (1), Eleutherocosus B (2) and Eleutherocosus C (3) together with seven known lignans (4 - 10) were isolated from the EtOAc-soluble extract of Eleutherococcus senticosus. Their structures were elucidated by the basis of spectroscopic and physicochemical analyses. All the isolates were evaluated for in vitro inhibitory activity against DGAT1 and DGAT2. Among them, compounds 1 - 3 exhibited the most potent inhibitory activity on DGAT1 with IC50 values of 71.4 ± 1.3, 79.1 ± 1.1 and 65.2 ± 1.2 μM, respectively.
- ISSN
- 1874-3900
- Publisher
- Elsevier
- Full Text Link
- http://dx.doi.org/10.1016/j.phytol.2023.03.007
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.