Enzymatic preparation of optically active 2-acetoxymethylglycidol, a new chiral building block in natural product synthesis
Cited 22 time in
- Title
- Enzymatic preparation of optically active 2-acetoxymethylglycidol, a new chiral building block in natural product synthesis
- Author(s)
- Young Bae Seu; Yung Hee Kho
- Bibliographic Citation
- Tetrahedron Letters, vol. 33, no. 46, pp. 7015-7016
- Publication Year
- 1992
- Abstract
- Asymmetric hydrolysis of geminally disubstituted achiral diacetate 2 with lipase PPL yielded optically active (R)-(-)-2-acetoxymethylglycidol 3 and its reduction gave compound 6, useful as the tert-alcohol chiral building block.
- ISSN
- 0040-4039
- Publisher
- Elsevier
- DOI
- http://dx.doi.org/10.1016/S0040-4039(00)60920-6
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
- Files in This Item:
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.